923604-01-7Relevant articles and documents
Synthesis of latonduine derivatives via intramolecular Heck?reaction
Putey, Aurélien,Joucla, Lionel,Picot, Laurent,Besson, Thierry,Joseph, Beno?t
, p. 867 - 879 (2007/10/03)
The synthesis of indole ring-fused benzazepinone series as latonduine derivatives has been developed via an intramolecular Heck reaction. The scope has been enlarged not only to indole moiety but also to pyrrolo and benzo[b]thiophene nuclei. Several derivatives prepared have been evaluated in vitro for their antiproliferative activities on breast cancer cell lines. Some of them showed promising cytotoxic activities.