92367-59-4

Basic information

• Product Name: 3,3-Dimethyl-3,4-dihydro-1H-quinolin-2-one
• Synonyms: 3,3-Dimethyl-3,4-dihydro-1H-quinolin-2-one;3,3-dimethyl-3,4-dihydroquinolin-2(1H)-one
• CAS NO: 92367-59-4
• Molecular Formula: C11H13NO
• Molecular Weight: 175.22702
• Mol File: 92367-59-4.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,3-Dimethyl-3,4-dihydro-1H-quinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dimethyl-3,4-dihydro-1H-quinolin-2-one(92367-59-4)
• EPA Substance Registry System: 3,3-Dimethyl-3,4-dihydro-1H-quinolin-2-one(92367-59-4)

Safety Data

• Hazardous Substances Data: 92367-59-4(Hazardous Substances Data)

Upstream product

• 31883-79-1 3-methyl-3,4-dihydroquinolin-2(1H)-one 
• 74-88-4 methyl iodide 
• 112565-71-6 1-(2-cyanoethyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline 
• 67-56-1 methanol 
• 1215765-41-5 1-chloro-3,4-dihydro-3,3-dimethylquinolin-2(1H)-one 
• 1215765-62-0 1-(4-methoxybenzyl)-3,4-dihydro-3,3-dimethylquinolin-2(1H)-one 
• 792122-85-1 1-[(4-methoxyphenyl)methyl]-3-methyl-3,4-dihydroquinolin-2-one 
• 792122-84-0 1-[(4-methoxyphenyl)methyl]-3,4-dihydroquinolin-2-one 
• 1308788-46-6 3-(2-bromophenyl)-2,2-dimethyl-N-(pyridin-2-ylmethyl)propanamide 
• 149080-24-0 3-(2-bromophenyl)-2,2-dimethylpropanoic acid 
• 6625-74-7 N-pivaloylaniline 
• 615-43-0 2-iodophenylamine 
• 95-51-2 o-chloroaniline 
• 615-36-1 2-bromoaniline 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND USES THEREOF

Provided herein are novel heterocyclic compounds, for example, compounds having Formula I, I-P, II, lI-P, or III. Also provided herein are pharmaceutical compositions comprising the compounds and methods of using the same, for example, in inhibiting aldehyde dehydrogenases and/or for treating various cancers, cancer metastasis, type 2 diabetes, pulmonary arterial hypertension (PAH) or neointimal hyperplasia (NIH).

Monoprotected l-Amino Acid (l-MPAA), Accelerated Bromination, Chlorination, and Iodination of C(sp2)?H Bonds by Iridium(III) Catalysis

Halogenated arenes are important structural motifs commonly found in biologically active molecules and used for a variety of transformations in organic synthesis. Herein, we report the mono-protected l-amino acid (l-MPAA) accelerated iridium(III)-catalyzed halogenation of (hetero)anilides at room temperature. This reaction constitutes the first example of an iridium(III)/l-MPAA-catalyzed general halogenation of (hetero)arenes through C(sp2)?H activation. Furthermore, we demonstrate the potential utility of our method through its use in the synthesis of a quinolone derivative.

Copper-catalyzed domino coupling reaction: An efficient method to synthesize oxindoles

An efficient and novel procedure for a copper catalyzed domino coupling reaction has been developed, which afforded various oxindoles in good to excellent yields with tolerance of various substituents. In addition, this method could be applied to synthesize horsfiline and coerulescine in few steps with high total yields. The Royal Society of Chemistry 2012.