923876-29-3

Basic information

• Product Name: C₁₆H₁₄N₄O₂
• Synonyms: C₁₆H₁₄N₄O₂
• CAS NO: 923876-29-3
• Molecular Weight: 294.313
• Mol File: 923876-29-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₄N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₄N₄O₂(923876-29-3)
• EPA Substance Registry System: C₁₆H₁₄N₄O₂(923876-29-3)

Safety Data

• Hazardous Substances Data: 923876-29-3(Hazardous Substances Data)

Downstream Products

• 1350474-54-2 N-(3-ethylbicyclo[2.2.1]hept-2-yl)-2-[3-(4-methoxyphenyl)-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl thio]acetamide 
• 1258381-20-2 C₁₉H₁₄N₄O₄S 
• 1258381-14-4 C₁₇H₁₁N₄O₂S^(1-)*K⁽¹⁺⁾ 

Relevant articles and documents

Benzo[e][1,2,4]triazino[2,3-c][1,2,3]triazin-2-ones electro-deficient heterocyclic compounds with promising anticancer activity

The synthesis and antitumor activity of substituted benzo[e][1,2,4]triazino[2,3-c][1,2,3]triazin-2-ones-novel electro-deficient tricyclic compounds-are described. These compounds were prepared by treatment of 3-(2-amino-3-R2-5-R3-phenyl)-6-R1-1,2,4-triazin-5(2H)-ones with sodium nitrite in acetic acid. Spectral properties of synthesized compounds were studied and compared with spectral data of known 3-R-8-R1-10-R2-2H-[1,2,4]triazino[2,3-c]quinazolin-2-ones. These compounds are promising antitumor agents. The most active anticancer compound 3d was studied in dose-depended anticancer activity assay and its selective growth inhibition against breast cancer MDA-MB-468 cell line was established (GI50=0.41 μm).