925230-63-3

Basic information

• Product Name: 1-methyl 4-(2-formylphenyl)-(Z)-but-2-en-1,4-dioate
• CAS NO: 925230-63-3
• Molecular Weight: 234.208
• Mol File: 925230-63-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl 4-(2-formylphenyl)-(Z)-but-2-en-1,4-dioate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl 4-(2-formylphenyl)-(Z)-but-2-en-1,4-dioate(925230-63-3)
• EPA Substance Registry System: 1-methyl 4-(2-formylphenyl)-(Z)-but-2-en-1,4-dioate(925230-63-3)

Safety Data

• Hazardous Substances Data: 925230-63-3(Hazardous Substances Data)

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 41502-62-9 methoxy-4-oxobut-2-enoic acid chloride 
• 3052-50-4 monomethyl maleate 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones

A straightforward two-step synthesis of benzoxepinones was developed via base-free phosphane-catalyzed Wittig reaction. 3-Methyl-1-phenyl-2-phospholene 1-oxide was used as a precatalyst and trimethoxysilane as a reducing agent. Additionally benzoic acid is employed as a catalyst to facilitate the reduction of the phosphane oxide. Mechanistic investigation revealed the formation of a coumarin as a side product, which was identified by 2D NMR experiments. First results of metabolic activity tests on the prepared benzoxepinones are reported.