926276-09-7

Basic information

• Product Name: Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-rel-
• Synonyms: Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-rel-;SFBZDQKMJLUZQF-OPRDCNLKSA-N
• CAS NO: 926276-09-7
• Molecular Formula: C13H21NO4
• Molecular Weight: 255.31
• Mol File: 926276-09-7.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-rel-(926276-09-7)
• EPA Substance Registry System: Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-rel-(926276-09-7)

Safety Data

• Hazardous Substances Data: 926276-09-7(Hazardous Substances Data)

Usage

Description

Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-relis a complex ester compound derived from cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-. It features a cyclopentane ring fused to a pyrrole ring, with two carboxylic acid functional groups and a 2-(1,1-diMethylethyl) ester group. The stereoisomeric form is characterized by the (1R,3aS,6aR)-reldesignation, which specifies the orientation of substituents in the molecule. This unique structure and properties may offer various potential applications in chemistry, pharmaceuticals, and materials science.

Uses

Used in Pharmaceutical Industry:
Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-relis used as a pharmaceutical intermediate for the synthesis of various drug molecules. Its unique structure and functional groups can be utilized to develop new therapeutic agents with specific biological activities.
Used in Chemical Research:
In the field of chemical research, Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-relserves as a valuable compound for studying the synthesis and reactions of complex organic molecules. Its unique structure can provide insights into the development of new synthetic routes and methodologies.
Used in Materials Science:
Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-diMethylethyl) ester, (1R,3aS,6aR)-relmay also find applications in materials science, particularly in the development of novel materials with specific properties. Its unique structure and functional groups can be exploited to create new materials with potential applications in various industries.

Upstream product

• 1227703-50-5 (3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-cyanide 
• 112626-50-3 (3aR,6aS)-octahydrocyclopenta[c]pyrrole hydrochloride 
• 1227703-21-0 (3aR,6aS)-1,3a,4,5,6,6a-hexahydrocyclopenta[c]pyrrole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 791572-14-0 (3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carboxylic acid 
• 1227703-21-0 (3aR,6aS)-1,3a,4,5,6,6a-hexahydrocyclopenta[c]pyrrole 
• 926276-08-6 (3aR,6aS)-tert-butyl hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 
• 124-38-9 carbon dioxide 
• 1093651-90-1 (S)-octahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-tert-butyl ester 1-ethyl ester 
• 1227704-10-0 (1S,3aR,6aS)-2-(tert-butoxycarbonyl)octahydrocyclopenta[c]pyrrole-1-carboxylic acid (S)-1,2,3,4-tetrahydro-1-naphthylammonium salt 
• 402960-06-9 (1S,3aR,6aS)-di-tert-butyl hexahydrocyclo-penta[c]pyrrol-1,2(1H)-dicarboxylate 
• 1451053-00-1 (R)-tert-butyl 2-(tert-butoxycarbonylamino)-2-((S)-2-methylenecyclopentyl)acetate 
• 1451052-99-5 C₁₃H₂₁NO₄ 
• 1053232-60-2 (1S,3aR,6aS)-hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-tert-butyl ester ethyl ester 

Downstream Products

• 597569-42-1 (1S,3aR,6aS)-2-(tert-butoxycarbonyl)octahydrocyclo-penta[c]pyrrole-1-carboxylic acid 
• 1053232-60-2 (1S,3aR,6aS)-hexahydro-cyclopenta[c]pyrrole-1,2-dicarboxylic acid 2-tert-butyl ester ethyl ester 
• 402960-06-9 (1S,3aR,6aS)-di-tert-butyl hexahydrocyclo-penta[c]pyrrol-1,2(1H)-dicarboxylate 
• 1205676-44-3 (1S,3αR,6αS)-octahydrocyclopenta[c]pyrrole-1-carboxylate hydrochloride 
• 926276-11-1 (1S,3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carboxylic acid 
• 1393524-02-1 (1R,3aS,6aR)-octahydrocyclopenta[c]pyrrole-1-carboxylic acid 

Relevant articles and documents

N-methyl-D-aspartate receptor modulators and methods of making and using same

Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.

Amide derivative, preparation method of amide derivative, and application of amide derivative to pharmacy

The invention provides an amide derivative, a preparation method of the amide derivative, and application of the amide derivative to pharmacy. The amide derivative compound is selected from one of the following structures. The compound can be used for preparing medicines in the fields of local anaesthesia or analgesia. (The formulas are as shown in the description).

Preparation method for bicyclic pyrrolidine intermediate of telaprevir

The invention discloses a preparation method for a bicyclic pyrrolidine intermediate of telaprevir. The intermediate is (1S,3alphaR,6alphaS)-octahydrocyclopenta[c]pyrrole-1-carboxylic acid-ethyl ester hydrochloride. The preparation method comprises the following steps: (1) with 3-azabicyclo[3.3.0]octane hydrochloride as a raw material, carrying out Boc2O protection under the action of inorganic base so as to obtain an intermediate 1; (2) dissolving the intermediate 1 in an organic solvent, adding chiral organic ligand, carrying out a reaction with lithium alkyl at -70 DEG C for 2 h under the protection of nitrogen and introducing dry carbon dioxide so as to obtain an intermediate 2; and (3) adding the intermediate 2 into a saturated hydrogen chloride ethanol solution and carrying out a heating reflux reaction for 3 h so as to obtain the target compound. The preparation method provided by the invention has the advantages of short synthesis route, low cost, high product yield and optical purity and easiness in realization of large-scale production.