92629-11-3 Usage
Description
5-BROMO-2-PHENYLOXAZOLE is a chemical compound characterized by the presence of a bromine atom at the 5th position and a phenyl group at the 2nd position of the oxazole ring. It is a heterocyclic compound with potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
5-BROMO-2-PHENYLOXAZOLE is used as a Δ5-desaturase inhibitor for the preparation of heterocyclic compounds. This application is significant in the development of pharmaceuticals, as Δ5-desaturase enzymes play a crucial role in the biosynthesis of certain fatty acids and other lipids, which are involved in various physiological processes and diseases.
In the preparation of heterocyclic compounds, 5-BROMO-2-PHENYLOXAZOLE serves as a key intermediate, enabling the synthesis of novel compounds with potential therapeutic properties. By inhibiting the Δ5-desaturase enzyme, these heterocyclic compounds can modulate lipid metabolism and potentially offer treatment options for various health conditions related to lipid imbalances.
Check Digit Verification of cas no
The CAS Registry Mumber 92629-11-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,6,2 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 92629-11:
(7*9)+(6*2)+(5*6)+(4*2)+(3*9)+(2*1)+(1*1)=143
143 % 10 = 3
So 92629-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H6BrNO/c10-8-6-11-9(12-8)7-4-2-1-3-5-7/h1-6H
92629-11-3Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE
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Page/Page column 97, (2021/06/04)
The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase ("D5D"). The compounds have a general Formula (I): wherein the variables of Formula (I) are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).
Composite tetraheteroarylenes and related higher cyclic oligomers of heteroarenes produced by palladium-catalyzed direct coupling
Fukuzumi, Keita,Nishii, Yu Ji,Miura, Masahiro
, p. 2030 - 2037 (2019/12/23)
Substantial research interests have been focused on cyclic π-conjugated molecules owing to their unique chemical and physical properties. By constructing hybrid aromatic arrays within these cyclic systems, new series of composite macrocycles would be prov
Synthesis of 2-Aryl- and 5-Alkyl-2-aryloxazoles from 2-Aryl-5-bromooxazoles
Kashima, Choji,Arao, Hideki
, p. 873 - 874 (2007/10/02)
2-Aryloxazoles, their 5-deuterio derivatives, and 5-alkyl-2-aryloxazoles are prepared in good yields from 2-aryl-5-bromooxazoles via halogen/metal exchange with butyllithium followed by treatment with water, methanol-O-d, or alkyl halides, respectively.
