926319-48-4

Basic information

• Product Name: 6-(phenylmethoxy)-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride
• Synonyms: 6-(phenylmethoxy)-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride
• CAS NO: 926319-48-4
• Molecular Weight: 513.033
• Mol File: 926319-48-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-(phenylmethoxy)-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(phenylmethoxy)-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride(926319-48-4)
• EPA Substance Registry System: 6-(phenylmethoxy)-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride(926319-48-4)

Safety Data

• Hazardous Substances Data: 926319-48-4(Hazardous Substances Data)

Upstream product

• 124955-27-7 8-(2-hydroxy-2-ethoxyacetyl)-6-(phenylmethoxy)-4H-1,4-benzoxazin-3-one 
• 56490-93-8 1,1-dimethyl-2-(4-methoxyphenyl)ethylamine hydrochloride 
• 869478-12-6 8-(2R)-oxirane-6-(phenylmethoxy)-2H-1,4-benzoxazine-3(4H)-one 
• 869478-11-5 6-benzyloxy-8-((R)-2-chloro-1-hydroxyethyl)-4H-benzo[1,4]-oxazin-3-one 
• 85628-47-3 4-Methoxy-(2-methyl-2-nitropropyl)benzol 
• 16066-97-0 1-nitro-1,1-dimethyl-2-(4-hydroxyphenyl]ethane 
• 56490-94-9 1-(2-amino-2-methylpropyl)-4-methoxybenzene 
• 926319-53-1 8-(bromoacetyl)-6-(phenylmethoxy)-2H-1,4-benzoxazin-3(4H)-one 
• 35144-39-9 1-(4-methoxyphenyl)-2-methylpropan-2-ol 
• 122-84-9 4-methoxybenzyl methyl ketone 

Downstream Products

• 869477-96-3 6-hydroxy-8-{(1R)-1-hydroxy-2-{[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino}ethyl}-4H-[1,4]benzoxazin-3-one hydrochloride 
• 869477-96-3 Olodaterol hydrochloride 

Relevant articles and documents

Preparation method of olodaterol and salts thereof

The invention relates to a preparation method of olodaterol and salts thereof, which comprises the following steps: in a solvent, carrying out oxidation and nucleophilic addition reaction on a compound shown in a formula I to obtain a compound shown in a

IMPROVED PROCESS FOR THE MANUFACTURE OF R-6-HYDROXY-8-[1-HYDROXY-2-[2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYLAMINOETHYL]-2H-1,4-BENZOXAZIN-3(4H)-ONE HYDROCHLORIDE

The present invention provides an improved process for the manufacture (R)-6- hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethyl-ethylamino-ethyl]-2H-1,4- benzoxazin-3(4H)-one, in high purity and high yield, through the use of 1,1-dimethyl-2- (4-met