92675-14-4
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Basic information
- Product Name: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid
- Synonyms: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid;Altiloxin B
- CAS NO:92675-14-4
- Molecular Formula: C15H23ClO4
- Molecular Weight: 302.79372
- EINECS: N/A
- Product Categories: N/A
- Mol File: 92675-14-4.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid(CAS DataBase Reference)
- NIST Chemistry Reference: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid(92675-14-4)
- EPA Substance Registry System: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid(92675-14-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 92675-14-4(Hazardous Substances Data)
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92675-14-4 Usage
Description
(1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid, also known as aliskiren, is a pharmaceutical compound that functions as a direct renin inhibitor. It is a medication specifically designed to treat high blood pressure by targeting and blocking the activity of renin, an enzyme that plays a crucial role in the production of a hormone responsible for increasing blood pressure. Aliskiren's mechanism of action involves the inhibition of renin, which in turn lowers blood pressure and helps in reducing the risk of heart attacks, strokes, and kidney problems. (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid is commonly marketed under the brand name Tekturna and is available for oral administration in tablet form.Uses
Used in Pharmaceutical Industry:Aliskiren is used as an antihypertensive agent for the treatment of high blood pressure. It is particularly prescribed for individuals who have not responded well to other blood pressure medications and is often used in combination with other antihypertensive drugs. By effectively lowering blood pressure, aliskiren contributes to the reduction of risks associated with cardiovascular and renal complications.
Check Digit Verification of cas no
The CAS Registry Mumber 92675-14-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,6,7 and 5 respectively; the second part has 2 digits, 1 and 4 respectively.Calculate Digit Verification of CAS Registry Number 92675-14:
(7*9)+(6*2)+(5*6)+(4*7)+(3*5)+(2*1)+(1*4)=154
154 % 10 = 4
So 92675-14-4 is a valid CAS Registry Number.
92675-14-4Upstream product
92675-14-4Downstream Products
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(1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid
