927407-98-5Relevant articles and documents
Synthesis and antimalarial activity of new isotebuquine analogues
Miroshnikova, Olga V.,Hudson, Thomas H.,Gerena, Lucia,Kyle, Dennis E.,Lin, Ai J.
, p. 889 - 896 (2007/10/03)
Amodiaquine (AQ) and tebuquine are 4-aminoquinoline antimalarials with Mannich base side chain and are highly effective against chloroquine (CQ)-resistant strains of Plasmodium falciparum. Clinical use of AQ has been severely restricted due to hepatoxicit