927692-09-9Relevant articles and documents
Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering
Leman, Luke J.,Weinberger, Dana A.,Huang, Zheng-Zheng,Wilcoxen, Keith M.,Ghadiri, M. Reza
, p. 2959 - 2966 (2007)
Ribosomes and nonribosomal peptide synthetases (NRPSs) carry out instructed peptide synthesis through a series of directed intermodular aminoacyl transfer reactions. We recently reported the design of coiled-coil assemblies that could functionally mimic t