927880-89-5 Usage
Chemical structure
A complex compound with multiple functional groups, including a benzene diamine core, a methyl group, a pyridinyl group, and a bulky N-methyl-4-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy] substituent.
Benzene diamine core
The central structure of the compound, consisting of a benzene ring with two amine (-NH2) groups attached.
Methyl group attachment
A methyl (-CH3) group is attached to the N1 position of the benzene diamine core.
Pyridinyl group
A heterocyclic compound with a nitrogen atom in a six-membered ring, linked to the compound.
Bulky substituent
A large N-methyl-4-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy] group that may influence the compound's properties and interactions.
Potential biological activity
The presence of various aromatic and heterocyclic moieties suggests that the compound may have interactions with biological targets, indicating possible pharmaceutical relevance.
Further research needed
To fully understand the properties, potential applications, and biological activity of this complex chemical, additional research and analysis are required.
Molecular weight
Approximately 369.32 g/mol (calculated from the chemical formula)
Appearance
The physical appearance of the compound is not provided, but it is likely a solid due to the presence of multiple aromatic and heterocyclic moieties.
Solubility
The solubility of the compound is not provided, but it may be soluble in organic solvents due to its lipophilic nature.
Stability
Information on the stability of the compound is not provided, but the presence of various functional groups may affect its stability under different conditions.
Reactivity
The reactivity of the compound is not provided, but the presence of amine, trifluoromethyl, and imidazol-2-yl groups may indicate potential reactivity with certain reagents or under specific conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 927880-89-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,7,8,8 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 927880-89:
(8*9)+(7*2)+(6*7)+(5*8)+(4*8)+(3*0)+(2*8)+(1*9)=225
225 % 10 = 5
So 927880-89-5 is a valid CAS Registry Number.
927880-89-5Relevant articles and documents
Discovery of RAF265: A Potent mut-B-RAF inhibitor for the treatment of metastatic melanoma
Williams, Teresa E.,Subramanian, Sharadha,Verhagen, Joelle,McBride, Christopher M.,Costales, Abran,Sung, Leonard,Antonios-Mccrea, William,McKenna, Maureen,Louie, Alicia K.,Ramurthy, Savithri,Levine, Barry,Shafer, Cynthia M.,MacHajewski, Timothy,Renhowe, Paul A.,Appleton, Brent A.,Amiri, Payman,Chou, James,Stuart, Darrin,Aardalen, Kimberly,Poon, Daniel
, p. 961 - 965 (2015/09/22)
Abrogation of errant signaling along the MAPK pathway through the inhibition of B-RAF kinase is a validated approach for the treatment of pathway-dependent cancers. We report the development of imidazo-benzimidazoles as potent B-RAF inhibitors. Robust in
SALTS OF BENZIMIDAZOLYL PYRIDYL ETHERS AND FORMULATIONS THEREOF
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, (2008/06/13)
Salts of benzimidazolyl pyridyl ethers are provided, particularly salts of { 1 -methyl-5- [2-(5-trifluoromethyl- 1 H-imidazol-2-yl)-pyridin-4-yloxy] - 1 H-benzoimidazol-2-yl } -(4- trifluoromethyl-phenyl)amine. Compositions and formulations including such
Substituted benzimidazoles and methods of preparation
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Page/Page column 20, (2008/06/13)
Methods for preparing new substituted benzimidazole compounds having formula (I) useful for treating kinase mediated disorders are provided wherein R1, R2, R3, R4, a, b, and c are defined herein
