928324-59-8

Basic information

• Product Name: 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride
• Synonyms: 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride;6-chloro-5-(trifluoromethyl)-3-Pyridinesulfonyl chloride
• CAS NO: 928324-59-8
• Molecular Formula: C₆H₂Cl₂F₃NO₂S
• Molecular Weight: 280
• Mol File: 928324-59-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride(928324-59-8)
• EPA Substance Registry System: 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride(928324-59-8)

Safety Data

• Hazardous Substances Data: 928324-59-8(Hazardous Substances Data)

Usage

General Description

6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride is a chemical compound with the molecular formula C7H3ClF3NO2S. It is a sulfonyl chloride derivative of pyridine, containing a chlorine atom and a trifluoromethyl group. 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride is commonly used as a reagent in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is a strong electrophile and can be used in reactions such as the introduction of the sulfonyl chloride functional group onto other molecules. Additionally, it can be used in the production of various heterocyclic compounds due to its pyridine core. 6-chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride is a versatile intermediate for the synthesis of a wide range of organic compounds and is valued for its ability to introduce the sulfonyl chloride functional group into various target molecules.

Upstream product

• 99368-67-9 2-chloro-5-nitro-3-(trifluoromethyl)pyridine 
• 99368-66-8 2-hydroxyl-5-nitro-3-(trifluoromethyl)pyridine 
• 887707-23-5 2-hydroxy-3-trifluoromethyl-5-(iodo)pyridine 
• 99368-68-0 6-chloro-5-(trifluoromethyl)pyridin-3-amine 

Relevant articles and documents

4-AMINO OR 4-ALKOXY-SUBSTITUTED ARYL SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS

Disclosed are compounds of Formula (I), Formula (II), or a salt thereof: Formula (I) Formula (II) which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (I), Formula (II) or their salts, and methods of treating pain disorders, cough, and itch using the same.

Acid secretion inhibitor

The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.