929022-84-4Relevant articles and documents
Design, synthesis and evaluation of phenethylaminoheterocycles as K v1.5 inhibitors
Johnson, James A.,Xu, Ningning,Jeon, Yoon,Finlay, Heather J.,Kover, Alexander,Conder, Mary L.,Sun, Huabin,Li, Danshi,Levesque, Paul,Hsueh, Mei-Mann,Harper, Timothy W.,Wexler, Ruth R.,Lloyd, John
, p. 3018 - 3022 (2014/06/24)
Phenethylaminoheterocycles have been prepared and assayed for inhibition of the Kv1.5 potassium ion channel as a potential approach to the treatment of atrial fibrillation. A diverse set of heterocycles were identified as potent Kv1.