929194-89-8

Basic information

• Product Name: Urea, N-[1-[[(4R)-4-(1-methylethyl)-1-cyclohexen-1-yl]methyl]-4-piperidinyl]-N'- 2-naphthalenyl-
• CAS NO: 929194-89-8
• Molecular Formula: C26H35N3O
• Molecular Weight: 405.583
• Mol File: 929194-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Urea, N-[1-[[(4R)-4-(1-methylethyl)-1-cyclohexen-1-yl]methyl]-4-piperidinyl]-N'- 2-naphthalenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N-[1-[[(4R)-4-(1-methylethyl)-1-cyclohexen-1-yl]methyl]-4-piperidinyl]-N'- 2-naphthalenyl-(929194-89-8)
• EPA Substance Registry System: Urea, N-[1-[[(4R)-4-(1-methylethyl)-1-cyclohexen-1-yl]methyl]-4-piperidinyl]-N'- 2-naphthalenyl-(929194-89-8)

Safety Data

• Hazardous Substances Data: 929194-89-8(Hazardous Substances Data)

Upstream product

• 503464-82-2 C₁₆H₁₉N₃O 
• 94369-75-2 (+)-(4R)-1-p-menthen-7-al 

Relevant articles and documents

Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists

The synthesis and biological evaluation of a series of 1-aryl-3-piperidin-4-yl-urea derivatives as small-molecule CXCR3 antagonists is described. SAR studies resulted in significant improvement of potency and physicochemical properties and established the key pharmacophore of the series, and led to the identification of 9t, which exhibits an IC50 of 16 nM in the GTPγS35 functional assay.