929468-09-7Relevant articles and documents
Synthesis, biological evaluation and 3D-QSAR study of novel 4,5-dihydro-1H-pyrazole thiazole derivatives as BRAFV600E inhibitors
Zhao, Meng-Yue,Yin, Yong,Yu, Xiao-Wei,Sangani, Chetan B.,Wang, Shu-Fu,Lu, Ai-Min,Yang, Li-Fang,Lv, Peng-Cheng,Jiang, Ming-Guo,Zhu, Hai-Liang
, p. 46 - 54 (2015/02/05)
Many reports implied that the BRAF serine/threonine kinase was mutated in various types of human tumors, which were related with cell growth, survival and differentiation. To provide new therapeutic opportunities, a series of novel 4,5-dihydro-1H-pyrazole