929612-39-5

Basic information

• Product Name: 1-phenyl-4-(4,4,4-trifluorobutyryloxy)-1,8-naphthyridin-2(1H)-one
• Synonyms: 1-phenyl-4-(4,4,4-trifluorobutyryloxy)-1,8-naphthyridin-2(1H)-one
• CAS NO: 929612-39-5
• Molecular Weight: 362.308
• Mol File: 929612-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-phenyl-4-(4,4,4-trifluorobutyryloxy)-1,8-naphthyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-4-(4,4,4-trifluorobutyryloxy)-1,8-naphthyridin-2(1H)-one(929612-39-5)
• EPA Substance Registry System: 1-phenyl-4-(4,4,4-trifluorobutyryloxy)-1,8-naphthyridin-2(1H)-one(929612-39-5)

Safety Data

• Hazardous Substances Data: 929612-39-5(Hazardous Substances Data)

Upstream product

• 406-91-7 4,4,4-trifluorobutanoyl chloride 
• 89109-17-1 4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)-one 

Downstream Products

• 929612-38-4 4-hydroxy-1-phenyl-3-(4,4,4-trifluorobutyryl)-1,8-naphthyridin-2(1H)-one 
• 929611-91-6 5-phenyl-3-(3,3,3-trifluoropropyl)-1H-pyrazolo[4,3-c][1,8]naphthyridin-4(5H)-one 

Relevant articles and documents

HETEROCYCLIC COMPOUND, AND PRODUCTION PROCESS AND USE THEREOF

The compound of the present invention is a novel compound which has a specific heterocycle skeleton, particularly a pyrazolonaphthyridine or pyrazoloquinoline skeleton having an organic group (e.g., a carbocycle and a heterocycle) bonding through an alkylene group at 3-position and a carbocycle bonding at 5-position and has a phosphodiesterase IV inhibitory activity. At least one of the ring (the carbocycle or the heterocycle) bonding at 3-position of the pyrazolonaphthyridine skeleton and the carbocycle bonding at 5-position may have a halogenated alkyl group and/or a halogenated alkoxy group as a substituent. Such a compound or a salt thereof is useful as a phosphodiesterase IV inhibitor and the like. According to the present invention, a novel compound having a high phosphodiesterase IV inhibitory effect can be provided.