930278-81-2

Basic information

• Product Name: (S)-2-(((4-chlorobenzyl)oxy)methyl)oxirane
• Synonyms: (S)-2-(((4-chlorobenzyl)oxy)methyl)oxirane
• CAS NO: 930278-81-2
• Molecular Weight: 198.649
• Mol File: 930278-81-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(((4-chlorobenzyl)oxy)methyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(((4-chlorobenzyl)oxy)methyl)oxirane(930278-81-2)
• EPA Substance Registry System: (S)-2-(((4-chlorobenzyl)oxy)methyl)oxirane(930278-81-2)

Safety Data

• Hazardous Substances Data: 930278-81-2(Hazardous Substances Data)

Upstream product

• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 57044-25-4 (R)-oxiranemethanol 
• 14289-63-5 1-chloro-4-(2-propenyloxymethyl)benzene 

Relevant articles and documents

Substrate stereocontrol in bromine-induced intermolecular cyclization: Asymmetric synthesis of pitavastatin calcium

A novel approach to synthesize pitavastatin calcium (1), an effective HMG-CoA reductase inhibitor, based on readily available and attractively functionalized (R)-3-chloro-1,2-propanediol is reported. This work highlights an intermolecular diastereoselective bromine-induced cyclization of homoallylic carbonate to meet stereochemical challenges in the synthesis of statins. An efficient route to a new triphenylphosphonium tetrafluoroborate salt of a quinoline core is also presented.