931086-24-7

Basic information

• Product Name: 3-(2-methoxy)-N-(8-quinolinyl)propanamide
• Synonyms: 3-(2-methoxy)-N-(8-quinolinyl)propanamide
• CAS NO: 931086-24-7
• Molecular Weight: 306.364
• Mol File: 931086-24-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(2-methoxy)-N-(8-quinolinyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-methoxy)-N-(8-quinolinyl)propanamide(931086-24-7)
• EPA Substance Registry System: 3-(2-methoxy)-N-(8-quinolinyl)propanamide(931086-24-7)

Safety Data

• Hazardous Substances Data: 931086-24-7(Hazardous Substances Data)

Upstream product

• 529-28-2 4-iodoanisol 
• 33757-46-9 8-(N-propionylamino)quinoline 
• 55001-09-7 methyl 3-(2-methoxyphenyl)propanoate 
• 15854-58-7 3-(2-methoxyphenyl)acrylic acid methyl ester 
• 135-02-4 ortho-anisaldehyde 
• 578-66-5 8-amino quinoline 
• 6342-77-4 2-methoxy-benzenepropanoic acid 

Downstream Products

• 1514926-97-6 1-(8-quinolinyl)-4-(2-methoxyphenyl)-azetidinone 

Relevant articles and documents

Palladium-Catalyzed β-C-H Arylation of Alkyl Carboxamides with Sterically Hindered Aryl Iodides Using ortho-Sulfinyl Aniline Auxiliaries

We disclose a pair of ortho-sulfinylaniline auxiliaries for palladium-catalyzed β-C-H arylation of alkyl carboxamides. Together, these auxiliaries offer a means to effect efficient β-methyl and methylene C-H bond arylation with sterically hindered aryl iodides. ortho-Methylsulfinylaniline (MSOA) enables efficient β-methyl C-H arylation of propanamide substrates with aryl iodides bearing various ortho-substituents including alkyl groups. ortho-Tosylsulfinylaniline (TSOA) enables β-methylene C-H arylation with ortho-substituted aryl iodides. Both amide-linked MSOA and TSOA auxiliaries can be easily removed to give ester products under relatively mild conditions.