931115-11-6

Basic information

• Product Name: 2-[(2S)-4-methyl-2-phenyl-1-piperazinyl]- 3-pyridinecarbonitrile
• Synonyms: 2-[(2S)-4-methyl-2-phenyl-1-piperazinyl]- 3-pyridinecarbonitrile
• CAS NO: 931115-11-6
• Molecular Formula: C₁₇H₁₈N₄
• Molecular Weight: 278
• Mol File: 931115-11-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(2S)-4-methyl-2-phenyl-1-piperazinyl]- 3-pyridinecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2S)-4-methyl-2-phenyl-1-piperazinyl]- 3-pyridinecarbonitrile(931115-11-6)
• EPA Substance Registry System: 2-[(2S)-4-methyl-2-phenyl-1-piperazinyl]- 3-pyridinecarbonitrile(931115-11-6)

Safety Data

• Hazardous Substances Data: 931115-11-6(Hazardous Substances Data)

Usage

Molecular weight

285.35 g/mol

Class

Piperazine derivatives

Type of compound

Pyridinecarbonitrile derivative

Piperazine group

A five-membered heterocyclic ring with two nitrogen atoms

Methyl-phenyl substituent

A phenyl group connected to a methyl group

Biological and pharmacological activities

Diverse, potentially useful in pharmaceutical synthesis

Potential applications

a. Medications for neurological disorders
b. Treatment of depression
c. Management of schizophrenia

Mechanism of action

Potential central nervous system agent

Research status

Requires further study and research to fully understand properties and potential applications

Upstream product

• 931115-12-7 (S)-1-(3-cyano-2-pyridyl)-4-methyl-2-phenylpiperazine oxalate 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 931115-08-1 (3S)-1-methyl-3-phenylpiperazine 

Downstream Products

• 1048380-67-1 2-[(2S)-4-methyl-2-phenyl-1-piperazinyl]-3-pyridinecarboxylic acid 
• 931115-12-7 (S)-1-(3-cyano-2-pyridyl)-4-methyl-2-phenylpiperazine oxalate 
• 931115-13-8 (S)-2-(4-methyl-2-phenylpiperazin-1-yl)-3-pyridinecarbaldehyde 

Relevant articles and documents

PROCESS FOR PRODUCING OPTICALLY ACTIVE PIPERAZINE COMPOUND

Provided is a method of producing optically active 1-methyl-3-phenylpiperazine of the formula (11) or salt thereof, comprising the following steps 1 to 4, or steps 5 to 7 and step 4, and a method of producing optically active mirtazapine via this method.

A METHOD FOR THE PREPARATION OF AN ENANTIOMER OF A TETRACYCLIC BENZAZEPINE

The present invention relates to a method for the preparation of mirtazapine and tetracyclic analogous compounds having substantial enantiomeric excess of the R or S form. The invention further relates to a novel intermediate and its use for the preparation of mirtazapine having a substantial enantiomeric excess of the R or S form. The method comprising the steps of a: providing a carboxylic acid compound according to Formula (I) having a substantial enantiomeric excess of the R or S form, b: converting the carboxylic acid group of compound I into a ketone group, producing a ketone compound of Formula (II), c: optionally reducing ketone compound II with a mild reduction agent to form the intermediate hydroxy compound of Formula (III) and d: forming the mirtazapine of Formula (IV) by reduction of the ketone compound II or of the hydroxy compound III using a strong reduction agent.