93134-38-4Relevant articles and documents
METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACID
-
Paragraph 0524; 0525; 0526, (2015/11/16)
In this method, an oligonucleotide is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R1, Y, Base, Z, Ar, R2, R3 and n are each as defined in Claim 1]. The
Oligodeoxyribonucleotide phosphorothioates: Substantial reduction of (N- 1)-mer content through the use of trimeric phosphoramidite synthons
Eleuteri, Alessandra,Capaldi, Daniel C.,Cole, Douglas L.,Ravikumar, Vasulinga T.
, p. 475 - 483 (2007/10/03)
Use of fully protected trimeric phosphoramidite synthons in the synthesis of oligonucleotide phosphorothioate shows a substantial reduction (>85%) in (n-1)-mer content as compared to oligomers synthesized through coupling of standard phosphoramidite monom
Improvements in Oligodeoxyribonucleotide Synthesis: Methyl N,N-Dialkylphosphoramidite Dimer Units for Solid Support Phosphite Methodology
Kumar, G.,Poonian, M.S.
, p. 4905 - 4912 (2007/10/02)
Two procedures for the synthesis of methyl N,N-dialkylphosphoramidite dinucleotides (dimer units) compatible with the current solid support phosphite methodology of oligodeoxynucleotide synthesis are described for the first time.In the first procedure a c