93148-78-8Relevant articles and documents
SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF
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Page/Page column 46, (2018/08/26)
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a piperidinyl-benzoimidazole structure which function as antagonists of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2), and their use as therapeutics for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related itch, anosmia, migraine event, and/or pain (e.g., neuropathic pain).
2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers
El Bakali, Jamal,Klupsch, Frederique,Guedin, Aurore,Brassart, Bertrand,Fontaine, Gaelle,Farce, Amaury,Roussel, Pascal,Houssin, Raymond,Bernier, Jean-Luc,Chavatte, Philippe,Mergny, Jean-Louis,Riou, Jean-Francois,Henichart, Jean-Pierre
scheme or table, p. 3434 - 3438 (2010/04/26)
The design and synthesis of 2,6-diphenylthiazolo[3,2-b][1,2,4]triazoles characterized by a large aromatic building block bearing cationic side chains are reported. These molecules are evaluated as telomeric G-quadruplex stabilizers and for their selectivi
Process for the synthesis of vinyl sulfoxides
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Page column 16, (2010/01/31)
The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides