93189-11-8

Basic information

• Product Name: (3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methanone
• Synonyms: (3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methanone
• CAS NO: 93189-11-8
• Molecular Weight: 199.252
• Mol File: 93189-11-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methanone(93189-11-8)
• EPA Substance Registry System: (3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methanone(93189-11-8)

Safety Data

• Hazardous Substances Data: 93189-11-8(Hazardous Substances Data)

Upstream product

• 625-82-1 2,4-dimethyl-1H-pyrrole 
• 98-88-4 benzoyl chloride 
• 613-89-8 2-Aminoacetophenone 
• 123-54-6 acetylacetone 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 18998-78-2 1-phenyl-hept-2-yn-1-one 
• 693-02-7 hex-1-yne 
• 5468-37-1 2-aminoacetophenone hydrochloride 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 536-74-3 phenylacetylene 
• 100-52-7 benzaldehyde 

Downstream Products

• 65-85-0 benzoic acid 
• 1030615-58-7 (3,5-bis(trifluoromethyl)phenyl)(7,9-dimethyl-1-phenyl-4,5-dihydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl)methanone 
• 1030615-60-1 (1-(3-aminopropyl)-3,5-dimethyl-1H-pyrrol-2-yl)(phenyl)methanone 
• 1030615-63-4 7,9-dimethyl-1-phenyl-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepine 
• 1030615-61-2 (Z)-7,9-dimethyl-1-phenyl-4,5-dihydro-3H-pyrrolo[1,2-a][1,4]diazepine 
• 1394285-07-4 Cu(5-phenyl-1,3,7,9-tetramethyldipyrrin)(bis(2-diphenylphosphinophenyl)ether)2 
• 1394285-06-3 Cu(5-phenyl-1,3,7,9-tetramethyldipyrrin)(PPh₃)2 
• 680222-61-1 3,3',5,5'-tetramethyl-6-phenylpyrromethene 
• 1030615-59-8 tert-butyl 3-(2-benzoyl-3,5-dimethyl-1H-pyrrol-1-yl)propylcarbamate 

Relevant articles and documents

Development of Gold-catalyzed [4+1] and [2+2+1]/[4+2] Annulations between Propiolate Derivatives and Isoxazoles

Two new gold-catalyzed annulations of isoxazoles with propiolates have been developed. Most isoxazoles follow an initial O attack on the alkyne to afford a [4+1] annulation product. This process results in a remarkable alkyne cleavage of initial propiolates. Unsubstituted isoxazoles proceed through an N attack step to yield formal [2+2+1]/[4+2] annulation products. These two annulation products arise initially from two seven-membered heterocyclic intermediates, which then lead to products.

Synthesis of 2-benzoylpyrrole derivatives via C-H functionalization adjacent to nitrogen of pyrrole

A direct transition-metal-free synthesis of 2-benzoylpyrrole derivatives from free (N-H) pyrroles and benzaldehyde has been developed. The benzoylation reaction at the 2 or 5-position of pyrrole proceeded well under the alkali metalation system and with 2

HETEROCYCLIC MODULATORS OF TGR5

The present invention relates to heterocyclic compounds useful as modulators of TGR5 and methods for the treatment of prevention of metabolic, cardiovascular, and inflammatory diseases.