93202-41-6

Basic information

• Product Name: 5-(chloroacetyl)-1,3-dihydro-2H-benzimidazol-2-one
• Synonyms: 5-(chloroacetyl)-1,3-dihydro-2H-benzimidazol-2-one;5-(2-chloroacetyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one
• CAS NO: 93202-41-6
• Molecular Formula: C9H7ClN2O2
• Molecular Weight: 210.62
• Mol File: 93202-41-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(chloroacetyl)-1,3-dihydro-2H-benzimidazol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(chloroacetyl)-1,3-dihydro-2H-benzimidazol-2-one(93202-41-6)
• EPA Substance Registry System: 5-(chloroacetyl)-1,3-dihydro-2H-benzimidazol-2-one(93202-41-6)

Safety Data

• Hazardous Substances Data: 93202-41-6(Hazardous Substances Data)

Upstream product

• 615-16-7 1,3-dihydro-2H-benzimidazol-2-one 
• 79-04-9 chloroacetyl chloride 
• 615-16-7 1H-benzimidazol-2-ol 

Downstream Products

• 1569065-87-7 5-(2-(4-fluoro-2-methylphenyl)thiazol-4-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 1569066-20-1 5-(2-(4-fluoro-2-[(2-methoxyethoxy)methyl]phenyl)thiazol-4-yl)-1H-benzo[d]imidazol-2(3H)-one 

Relevant articles and documents

KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE

The present invention is directed to kinase inhibitor compounds having the following structure: or a stereoisomer, pharmaceuticallyacceptable salt, oxide, or solvate thereof, where R1, R2, X, n, R3, Y, Z, R4, R

COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS

Compounds and compositions are presented that inhibit K-ras, and especially mutant K-ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.

MIF INHIBITORS

The present invention relates to the use of specific benzimidazolone analogues and derivatives to inhibit the cytokine or biological activity of macrophage migration inhibitory factor (MIF), and diseases or conditions wherein MIF cytokine or biological activity is implicated. Novel benzimidazole analogues and derivatives are also provided.