93242-59-2 Usage
Chemical class
Fluoroquinolone antibiotic
Molecular structure
Consists of a quinoline core with a carboxylic acid group and various substituents, including an ethyl group, difluoro groups, and an imidazole ring.
Mechanism of action
Inhibits bacterial DNA gyrase and topoisomerase IV, disrupting bacterial DNA replication and transcription.
Effectiveness
Active against a wide range of bacterial infections.
Bactericidal effects
Penetrates and disrupts bacterial cell membranes, leading to cell death.
Potential side effects
Should be used with caution and under the guidance of a healthcare professional due to possible side effects.
Usage
Prescribed for treating bacterial infections, particularly those caused by gram-negative and gram-positive bacteria.
Precautions
May not be suitable for all patients, and healthcare professionals should consider individual patient factors and potential drug interactions before prescribing.
Dosage and administration
Dosage and administration should be determined by a healthcare professional based on the patient's condition, severity of infection, and other relevant factors.
Check Digit Verification of cas no
The CAS Registry Mumber 93242-59-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,2,4 and 2 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 93242-59:
(7*9)+(6*3)+(5*2)+(4*4)+(3*2)+(2*5)+(1*9)=132
132 % 10 = 2
So 93242-59-2 is a valid CAS Registry Number.
93242-59-2Relevant articles and documents
Synthesis of Antimicrobial Agents. 1. Syntheses and Antibacterial Activities of 7-(Azole substituted)quinolones
Uno, Toshio,Takamatsu, Masanori,Inoue, Yoshimasa,Kawahata, Yoshihiro,Iuchi, Koji,Tsukamoto, Goro
, p. 2163 - 2169 (1987)
A series of 6-fluoro- and 6,8-difluoro-7-(azole substituted)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids were prepared.Structure-activity relationship studies indicated that the antibacterial potency was better when the 6,8-substituents were fluorine atoms and the 7-substituent was either 1-imidazolyl, 20, or 4-methyl-1-imidazolyl, 25.From the results of studies on pharmacokinetic profile and toxicity, 20 and 25 were found to possess excellent antibacterial activities and to show high blood levels after oral administration to mice with low toxicity.