93287-12-8Relevant articles and documents
Amidino derivatives useful as nitric oxide synthase inhibitors
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, (2008/06/13)
The current invention discloses useful pharmaceutical compositions containing amidino derivative useful as nitric oxide synthase inhibitors.
HALOSILANES IN THE SYNTHESIS OF N-(HALOMETHYL) DERIVATIVES OF LACTAMS, N-METHYLCARBOXAMIDES, AND IMIDES
Orlova, N.A.,Shipov, A.G.,Savost'yanova, I.A.,Baukov, Yu.I.
, p. 1875 - 1881 (2007/10/02)
Methods are proposed for the synthesis of N-(halomethyl) derivatives of lactams, N-methylcarboxamides, and imides with the use of the paraform-chlorotrimethylsilane system and the replacement of the trimethylsiloxy group by halogen and of halogen by halogen by the action of halotrimethylsilanes or acetyl bromide.The reactions of N-(chloromethyl)lactams with carboxylic anhydrides lead to N-(acyloxymethyl)lactams.