933752-89-7

Basic information

• Product Name: 6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde
• Synonyms: 6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde;IMidazo[1,2-a]pyridine-3-carboxaldehyde, 6-Methyl-
• CAS NO: 933752-89-7
• Molecular Formula: C9H8N2O
• Molecular Weight: 160.17
• Mol File: 933752-89-7.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Density: 1.21 g/cm³
• Storage Temp.: 2-8°C
• PKA: 4.46±0.50(Predicted)
• CAS DataBase Reference: 6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde(933752-89-7)
• EPA Substance Registry System: 6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde(933752-89-7)

Safety Data

• Hazardous Substances Data: 933752-89-7(Hazardous Substances Data)

Usage

General Description

6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde is a chemical compound that belongs to the class of aldehydes. It is commonly used in the field of organic chemistry for various synthetic applications. 6-Methylimidazo[1,2-a]pyridine-3-carbaldehyde is a key intermediate in the synthesis of many pharmaceutical compounds and is utilized in the production of various fine chemicals. It is also known for its potential as a flavoring agent in the food industry, where it is used in small amounts to give specific taste and aroma to certain food products. However, it is important to handle this chemical with caution, as aldehydes can be irritants and may have adverse effects if not used properly.

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 874-38-4 6-methylimidazo[1,2-a]pyridine 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 624-67-9 Propargylic aldehyde 
• 2065-75-0 2-Bromo-malonaldehyde 

Relevant articles and documents

Microwave-assisted synthesis of 3-formyl substituted imidazo[1,2-a]pyridines

An efficient, metal-free method for the synthesis of 3-formyl imidazo[1,2-a]pyridines is reported. The method utilises commercially available substrates and features a broad substrate scope. The intermediate enamine was isolated and a plausible reaction mechanism proposed.

Heterogeneous gold(I)-catalysed annulation between 2-aminopyridines and propiolaldehydes leading to 3-acylimidazo[1,2-a]pyridines

The heterogeneous annulation between 2-aminopyridines and propiolaldehydes was achieved in CH2Cl2 at 25 °C in the presence of 3 mol% of MCM-41-immobilised phosphine gold(I) complex (MCM-41-PPh3-AuCl) and AgSbF6

Aerobic iron(III)-catalyzed direct formylation of imidazo[1,2-a]pyridine using DMSO as carbon source

A novel and efficient iron(III)-catalyzed C3-formylation reaction of imidazo[1,2-a]pyridine in an oxygen atmosphere has been developed. The method is conducted in dimethyl sulfoxide (DMSO), which serves as both the carbonyl carbon source and solvent, in the presence of acetic acid to directly generate structurally diverse 3-formylimidazo[1,2-a]pyridine derivatives in moderate to good yields.