934175-49-2Relevant articles and documents
Antimicrobial Evaluation, Synthesis, and Characterization of Some 1-(5-((1H-Pyrazol-1-yl)methyl)-2-aryl-1,3,4-oxadiazol-3(2H)-yl)ethanone Derivatives
Alghamdi, Saad,Almehmadi, Mazen M.,Asif, Mohammad
, p. 577 - 582 (2022/01/26)
Ethyl 2-(1H-pyrazol-1-yl)acetate (1) was synthesized by the reaction of ethyl chloro acetate with 1H-pyrazole. Compound (1) was refluxed with hydrazine hydrate to get 2-(1H-pyrazol-1-yl) acetohydrazide (2). N'-arylidine-2-(1H-pyrazol-1-yl)acetohydrazide d
Synthesis of N- and C-azolyl-substituted pyrazolo[1,5-a]pyrimidines by recyclization of pyrimidinium salts
Danagulyan, Gevorg G.,Tumanyan, Araksya K.,Attaryan, Oganes S.,Tamazyan, Rafael A.,Danagulyan, Anna G.,Ayvazyan, Armen G.
, p. 483 - 490 (2015/10/19)
We studied the reaction of 2-(ethoxycarbonyl)methyl-1,4,6-trimethylpyrimidinium iodide with hydrazides of N-azolyl- and C-pyrazolyl-substituted carboxylic acids, which were synthesized by reacting the respective esters with hydrazine hydrate. This reaction was shown to result in recyclization and formation of ethyl 2-(pyrazolylalkyl)- and 2-(azolylalkyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine- 3-carboxylates. Besides pyrazolopyrimidines, the separation of reaction mixture provided in some cases also another recyclization product, 2-hydroxy-5,7-dimethylpyrazolo[1,5-a]pyrimidine.