93444-55-4Relevant articles and documents
Synthesis and protein tyrosine phosphatase 1B-Inhibitory activity of chalcones
Zhao, Fei,Zhao, Qing-Jie,Zhang, Da-Zhi,Jin, Yong-Sheng,Zhang, Wei
experimental part, p. 5339 - 5342 (2012/06/30)
Protein tyrosine phosphatase 1B (PTP1B) is an effective target for the treatment of type 2 diabetes and obesity. So far less work has been conducted in the structure-activity relationship of the PTP1B inhibitory activity of chalcones. In this work, a libr