93504-92-8 Usage
Description
BUTANEDIOIC ACID, 2-HYDROXY-3-METHYL-, DIETHYL ESTER, also known as Diethyl 2-Hydroxy-3-methylbutanedioate, is an organic compound that serves as an intermediate in the synthesis of various chemical compounds. It is characterized by its ester functional group and its ability to participate in various chemical reactions.
Uses
Used in Pharmaceutical Industry:
Diethyl 2-Hydroxy-3-methylbutanedioate is used as an intermediate in the synthesis of 5-Methyl-2'-deoxy Cytidine-13C,15N2 (M295904), which is an isotopic analog of 5-Methyl-2'-deoxy Cytidine (M295900). This isotopic analog is a Cytidine (C998300) analog and also an isostere of Thymidine (T412000), making it valuable for research and development in the pharmaceutical industry.
Used in Research and Development:
Diethyl 2-Hydroxy-3-methylbutanedioate is utilized in the development of new compounds and drugs, particularly in the synthesis of isotopic analogs and isosteres. Its unique chemical properties make it a valuable component in the creation of novel pharmaceutical agents and research tools.
Check Digit Verification of cas no
The CAS Registry Mumber 93504-92-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,5,0 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 93504-92:
(7*9)+(6*3)+(5*5)+(4*0)+(3*4)+(2*9)+(1*2)=138
138 % 10 = 8
So 93504-92-8 is a valid CAS Registry Number.
93504-92-8Relevant articles and documents
Synthesis of erythro-2-Hydroxy-3-methylbutane-1,4-dioic Acid
Bhat, K. S.,Dixit, K. N.,Rao, A. S.
, p. 509 - 512 (2007/10/02)
Reduction of ethyl 3-methyl-2-oxobutane-1,4-dioate (3) with sodium borohydride furnishes a 6:1 mixture of ethyl erythro-2-hydroxy-3-methylbutane-1,4-dioate (8) and ethyl threo-2-hydroxy-3-methylbutane-1,4-dioate (18).Hydrolysis of this mixture with aq. hydrochloric acid gives a mixture of acids from which pure erythro-2-hydroxy-3-methylbutane-1,4-dioic acid (4) has been isolated.The stereochemistry of 4 has been establishrd by PMR and by transforming it to the anhydride, erythro-dihydro-3-acetyloxy-4-methyl-2,5-furandione (26).
