935547-68-5Relevant articles and documents
A straightforward protocol for the solution-phase parallel synthesis of ceramide analogues
Grijalvo, Santiago,Matabosch, Xavier,Llebaria, Amadeu,Delgado, Antonio
, p. 150 - 155 (2008/09/18)
A simple solution-phase protocol for the synthesis of ceramide analogues from easily accessible enantiopure scaffolds is disclosed. The method relies on the use of nucleophilic thiolates or phenoxides and appropriate supported reagents or scavengers to gi
Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues
Grijalvo, Santiago,Bedia, Carmen,Triola, Gemma,Casas, Josefina,Llebaria, Amadeu,Teixido, Jordi,Rabal, Obdulia,Levade, Thierry,Delgado, Antonio,Fabrias, Gemma
, p. 69 - 84 (2007/10/03)
The synthesis of novel N-acylethanolamines and their use as inhibitors of the aCDase is reported here. The compounds are either 2-oxooctanamides or oleamides of sphingosine analogs featuring a 3-hydroxy-4,5-hexadecenyl tail replaced by ether or thioether
