93635-76-8

Basic information

• Product Name: D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester
• Synonyms: D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester;D-Arabinonic acid, 2-C-Methyl-4,5-O-(1-Methylethylidene)-,ethyl;(2S,3R)-3-((4R)-2,2-DiMethyldioxolan-4-yl)-2-Methyl-2,3-dihydroxypropanoic acid ethyl ester;4,5-O-isopropylidene-2-C-Methyl-D-arabinonate;ethyl (2S,3R)-3-[(4R)-2,2-diMethyl-1,3-dioxolan-4-yl]-2,3-dihydroxy-2-Methyl-propanoate;(2S,3R)-Ethyl 3-((R)-2,2-diMethyl-1,3-dioxolan-4-yl)-2,3-dihydroxy-2-Methylpropanoate;3-(2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,3-dihydroxy-2-methyl-propionic acid ethyl ester;-2,3-dihydroxy-2-methylpropanoate
• CAS NO: 93635-76-8
• Molecular Formula: C₁₁H₂₀O₆
• Molecular Weight: 248.273
• EINECS: 1592732-453-0
• Product Categories: API intermediates
• Mol File: 93635-76-8.mol
• Article Data: 18

Chemical Properties

• Melting Point: 75.0-75.5℃
• Boiling Point: 361.451°C at 760 mmHg
• Flash Point: 133.189°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.475
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.29±0.29(Predicted)
• CAS DataBase Reference: D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester(93635-76-8)
• EPA Substance Registry System: D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester(93635-76-8)

Safety Data

• Hazardous Substances Data: 93635-76-8(Hazardous Substances Data)

Usage

Uses

2-C-Methyl-4,5-O-(1-methylethylidene)-D-arabinonic Acid Ethyl Ester can be?utilized for the synthesis of2''-deoxy-2''-fluoro-2''-C-methylcytidine (I) (PSI-6130), which is a potent and selective inhibitor of HCV NS5B polymerase. This product also has potential applications for the synthesis of related antiviral agents.

InChI:InChI=1/C11H20O6/c1-5-15-9(13)11(4,14)8(12)7-6-16-10(2,3)17-7/h7-8,12,14H,5-6H2,1-4H3/t7-,8-,11+/m1/s1

Upstream product

• 81997-75-3 ethyl (Z)(R)-4,5-O-isopropylidene-4,5-dihydroxy-2-methylpent-2-enoate 
• 21382-82-1 (carbethoxyethylidene)triphenylphosphorane 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 130606-67-6 C₁₁H₁₈O₄ 
• 81997-76-4 (S,E)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylpropionic acid ethyl ester 
• 81997-75-3 ethyl trans-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-D-glycero-pent-2-enonate 
• 93714-03-5 ethyl trans-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate 
• 93714-02-4 ethyl cis-2,3-dideoxy-4,5-O-isopropylidene-2-C-methyl-DL-glycero-pent-2-enonate 

Downstream Products

• 879551-04-9 (3R,4R,5R)-3?fluoro?4?hydroxy?5?(hydroxymethyl)?3?methyltetrahydrofuran?2?one 
• 874638-80-9 ((2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-tetrahydrofuran-2-yl)methyl benzoate 
• 879551-01-6 (4S,5R)-ethyl-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-meth-yl-1,3,2-dioxathiolane-4-carboxylate 2,2-dioxide 
• 1596350-90-1 C₂₂H₂₄N₄O₃ 
• 1596350-94-5 C₂₃H₂₆N₆O₃ 
• 1596350-95-6 C₂₅H₂₆N₈O₃ 
• 1403574-26-4 C₂₀H₁₇N₃O₆ 
• 1596350-41-2 C₂₀H₂₁N₃O₄ 
• 1596350-43-4 C₂₇H₂₈N₆O₃S 
• 1596350-44-5 C₂₆H₂₇N₇O₃ 
• 1613589-83-5 C₆₈H₆₉F₂N₆O₁₀P 

Relevant articles and documents

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Method for preparing intermediate of Sofosbuvir

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