936834-79-6

Basic information

• Product Name: 5-hydroxy-3-methyl-1-(3-nitrophenyl)-1H-pyrazole
• Synonyms: 5-hydroxy-3-methyl-1-(3-nitrophenyl)-1H-pyrazole
• CAS NO: 936834-79-6
• Molecular Weight: 219.2
• Mol File: 936834-79-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-3-methyl-1-(3-nitrophenyl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-3-methyl-1-(3-nitrophenyl)-1H-pyrazole(936834-79-6)
• EPA Substance Registry System: 5-hydroxy-3-methyl-1-(3-nitrophenyl)-1H-pyrazole(936834-79-6)

Safety Data

• Hazardous Substances Data: 936834-79-6(Hazardous Substances Data)

Upstream product

• 51516-96-2 3-nitrophenylhydrazine hydrochloride 
• 105-45-3 acetoacetic acid methyl ester 
• 585-79-5 m-nitrobromobenzene 
• 132712-71-1 5-hydroxy-3-methylpyrazole 

Downstream Products

• 1022798-38-4 4-isopropylidene-3-methyl-1-(3-nitrophenyl)-1H-pyrazol-5(4H)-one 
• 210099-46-0 3,6-Dimethyl-1-(3-nitro-phenyl)-5-phenyl-1H-pyrano[2,3-c]pyrazol-4-one 
• 210099-43-7 3-Methyl-1-(3-nitro-phenyl)-6-phenyl-1H-pyrano[2,3-c]pyrazol-4-one 
• 210099-60-8 1-[5-Hydroxy-3-methyl-1-(3-nitro-phenyl)-1H-pyrazol-4-yl]-2-methyl-propenone 
• 210099-62-0 (E)-1-[5-Hydroxy-3-methyl-1-(3-nitro-phenyl)-1H-pyrazol-4-yl]-3-phenyl-propenone 

Relevant articles and documents

Preparation method of pyrazole compound

The invention discloses a preparation method of a pyrazole compound, namely 1-(3-nitrophenyl)-3-methyl-1H-pyrazole-5-chloride. The preparation method comprises the following steps: with ethyl acetoacetate as an initial raw material, performing ring closing, condensation and chlorination to obtain the target product. The compound is an important medical intermediate.

Cyclic and acyclic products from the reactions between methyl 3-oxo-butanoate and aryl-hydrazines

The mol-ecules of methyl 3-(2-nitro-phenyl-hydrazono)-butan-oate, C11H13N3O4, (I), and methyl 3-(2,4-dinitro-phenyl-hydrazono)butanoate, C11H12N4O6, (II), both prepared from methyl 3-oxobutanoate and the corresponding nitro-phenyl-hydrazine, exhibit polarized mol-ecular electronic structures; in each of (I) and (II), the mol-ecules are linked into chains by a single C - H...O hydrogen bond. The mol-ecules of 5-hydroxy-3-methyl-1-phenyl-1H- pyrazole, C10H10N2O, (III), prepared by the reaction of methyl 3-oxobutanoate and phenyl-hydrazine, are linked into chains by a single O - H...N hydrogen bond. The reaction between methyl 3-oxobutanoate and 3-nitro-phenyl-hydrazine yields 5-hydr-oxy-3-methyl-1-(3-nitro-phen-yl)-1H-pyrazole, (IV), which when crystallized from acetone yields 4-isopropyl-idene-3-methyl-1-(3-nitro-phen-yl)- 1H-pyrazol-5(4H)-one, C13H13N3O3, (V). International Union of Crystallography 2007.