936949-47-2

Basic information

• Product Name: 4-[2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2H-pyrazol-3-yl]-butyric acid
• CAS NO: 936949-47-2
• Molecular Weight: 511.251
• Mol File: 936949-47-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2H-pyrazol-3-yl]-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2H-pyrazol-3-yl]-butyric acid(936949-47-2)
• EPA Substance Registry System: 4-[2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2H-pyrazol-3-yl]-butyric acid(936949-47-2)

Safety Data

• Hazardous Substances Data: 936949-47-2(Hazardous Substances Data)

Upstream product

• 886-35-1 3,5-bis(trifluoromethyl)phenylhydrazine 
• 936948-71-9 4-[2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2H-pyrazol-3-yl]-but-3-yn-1-ol 
• 936947-43-2 2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2,4-dihydro-pyrazol-3-one 
• 936948-12-8 1-(3,5-bis-trifluoromethyl-phenyl)-5-bromo-3-(3,5-dichloro-phenyl)-1H-pyrazole 
• 936946-45-1 4-[2-(3,5-bis-trifluoromethyl-phenyl)-5-(3,5-dichloro-phenyl)-2H-pyrazol-3-yl]-butan-1-ol 

Relevant articles and documents

Diaryl substituted pyrazoles as potent CCR2 receptor antagonists

We have identified and synthesized a series of diaryl substituted pyrazoles as potent antagonists of the chemokine receptor subtype 2. Structure-activity relationship studies directed toward improving the potency led to the discovery of 23 (IC50/sub