93788-86-4

Basic information

• Product Name: p-methoxybenzyl 2-(3-phenylacetamido-4-benzenesulfonylthio-2-azetidinon-1-yl)-3-methyl-3-butenoate
• Synonyms: p-methoxybenzyl 2-(3-phenylacetamido-4-benzenesulfonylthio-2-azetidinon-1-yl)-3-methyl-3-butenoate
• CAS NO: 93788-86-4
• Molecular Weight: 594.709
• Mol File: 93788-86-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: p-methoxybenzyl 2-(3-phenylacetamido-4-benzenesulfonylthio-2-azetidinon-1-yl)-3-methyl-3-butenoate(CAS DataBase Reference)
• NIST Chemistry Reference: p-methoxybenzyl 2-(3-phenylacetamido-4-benzenesulfonylthio-2-azetidinon-1-yl)-3-methyl-3-butenoate(93788-86-4)
• EPA Substance Registry System: p-methoxybenzyl 2-(3-phenylacetamido-4-benzenesulfonylthio-2-azetidinon-1-yl)-3-methyl-3-butenoate(93788-86-4)

Safety Data

• Hazardous Substances Data: 93788-86-4(Hazardous Substances Data)

Upstream product

• 93788-82-0 C₂₄H₂₄N₂O₄S 
• 98-59-9 p-toluenesulfonyl chloride 
• 98231-55-1 p-methoxybenzyl 2-(2-benzothiazolyldithio)-α-(1-methylethenyl)-4-oxo-3-phenacetamido-1-azetidineacetate 
• 618-41-7 Benzenesulfinic acid 
• 41475-98-3 S-(benzo[d]thiazol-2-yl) benzenesulfonothioate 
• 873-55-2 sodium benzenesulfonate 
• 98231-55-1 2-[(2R,3R)-2-(Benzothiazol-2-yldisulfanyl)-4-oxo-3-phenylacetylamino-azetidin-1-yl]-3-methyl-but-3-enoic acid 4-methoxy-benzyl ester 

Downstream Products

• 95361-36-7 C₃₀H₂₉ClN₂O₇S₂ 

Relevant articles and documents

PROCESS FOR PRODUCING 3-CHLOROMETHYL-3-CEPHEM DERIVATIVE

An industrially advantageous process for producing 3-chloromethyl-3-cephem derivative crystals. The process for 3-chloromethyl-3-cephem derivative production comprises: a first step in which a thiazolineazetidinone derivative (1) is reacted with a sulfonyl halide (2) in the presence of an acid in a solvent to obtain an azetidinone derivative (3); a second step in which the azetidinone derivative (3) is reacted with a chlorinating agent in an organic solvent to obtain a chlorinated azetidinone derivative (4); and a third step in which the chlorinated azetidinone derivative (4) is reacted with an alcoholate (5) at a pH of 8 or lower in a solvent comprising an alcohol and an ether and a 3-chloromethyl-3-cephem derivative (6) is recovered in the form of crystals.

Process for preparation of azetidinone derivatives

A process for preparing an azetidinone derivative represented by the formula STR1 wherein R1 is hydrogen, halogen or lower alkoxy, R2 is hydrogen, halogen, lower alkoxy, amino or a group STR2 (in which R5 is substituted or

Process for preparation of azetidinone derivatives

A process for preparing an azetidinone derivative represented by the formula STR1 wherein R1 is hydrogen, halogen or lower alkoxy, R2 is hydrogen, halogen, lower alkoxy, amino or a group STR2 (in which R5 is substituted or unsubstituted phenyl, substituted or unsubstituted phenylmethyl, substituted or unsubstituted phenoxymethyl, or substituted or unsubstituted benzoyl), or R1 and R2, when taken together, are carbonyl, R3 is substituted or unsubstituted phenyl, and R4 is hydrogen, optionally substituted hydrocarbon residue or acyl, silyl, sulfonyl or phosphonyl derived from inorganic acid or organic acid, the process comprising reacting a dithioazetidinone derivative represented by the formula STR3 wherein R1, R2 and R4 are as defined above and R9 is substituted or unsubstituted, nitrogen-containing aromatic heterocyclic residue with a compound represented by the formula wherein R3 is defined above.