938045-21-7Relevant articles and documents
Synthesis of functionalized pyridazin-3(2 H)-ones via selective bromine-magnesium exchange and lactam directed ortho C-H magnesiation
Verhelst, Tom,Maes, Jens,Liu, Zuming,Sergeyev, Sergey,Maes, Bert U. W.
experimental part, p. 6670 - 6677 (2011/10/18)
Selective bromine-magnesium exchange on 2-benzyl-5-bromo-4- methoxypyridazin-3(2H)-one could be achieved when MesMgBr was used as reagent. With more nucleophilic RMgCl species (R = Bu, i-Pr, Ph) both nucleophilic addition-elimination at C-4 and bromine-ma