938185-98-9Relevant articles and documents
Azepinone-containing tetrapeptide analogues of melanotropin lead to selective h MC4R agonists and h MC5R antagonist
Van Der Poorten, Olivier,Fehér, Krisztina,Buysse, Koen,Feytens, Debby,Zoi, Ioanna,Schwartz, Steven D.,Martins, José C.,Tourwé, Dirk,Cai, Minying,Hruby, Victor J.,Ballet, Steven
, p. 192 - 197 (2015/03/04)
To address the need for highly potent, metabolically stable, and selective agonists, antagonists, and inverse agonists at the melanocortin receptor subtypes, conformationally constrained indolo- and benzazepinone residues were inserted into the α-MSH phar
