93885-69-9 Usage
Description
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4(1H,3H)-pyrimidinedione is a chemical compound that is an impurity of Trimethoprim, an antibacterial agent.
Used in Pharmaceutical Industry:
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4(1H,3H)-pyrimidinedione is used as an impurity in the production of Trimethoprim, an antibacterial agent, for its potential role in the development and efficacy of the drug.
Check Digit Verification of cas no
The CAS Registry Mumber 93885-69-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,8,8 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 93885-69:
(7*9)+(6*3)+(5*8)+(4*8)+(3*5)+(2*6)+(1*9)=189
189 % 10 = 9
So 93885-69-9 is a valid CAS Registry Number.
93885-69-9Relevant articles and documents
Synthesis of functionalized diarylmethanes via a copper-catalyzed cross-coupling of arylmagnesium reagents with benzylic phosphates
Kofink, Christiane C.,Knochel, Paul
, p. 4121 - 4124 (2007/10/03)
A combination of copper chloride, triethyl phosphite, and tetrabutylammonium iodide is a very efficient catalytic system for the synthesis of polyfunctionalized diarylmethanes, using the cross-coupling reaction of arylmagnesium halides with benzylic phosphates. The antibiotic Trimethoprim has been prepared using this Cu(I)-catalyzed cross-coupling in 52% overall yield (four steps).