939055-53-5

Basic information

• Product Name: N-(4-(dimethylamino)phenyl)-6-oxo-1-(prop-2-ynyl)-1,6-dihydropyridine-2-carboxamide
• Synonyms: N-(4-(dimethylamino)phenyl)-6-oxo-1-(prop-2-ynyl)-1,6-dihydropyridine-2-carboxamide
• CAS NO: 939055-53-5
• Molecular Weight: 295.341
• Mol File: 939055-53-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-(dimethylamino)phenyl)-6-oxo-1-(prop-2-ynyl)-1,6-dihydropyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(dimethylamino)phenyl)-6-oxo-1-(prop-2-ynyl)-1,6-dihydropyridine-2-carboxamide(939055-53-5)
• EPA Substance Registry System: N-(4-(dimethylamino)phenyl)-6-oxo-1-(prop-2-ynyl)-1,6-dihydropyridine-2-carboxamide(939055-53-5)

Safety Data

• Hazardous Substances Data: 939055-53-5(Hazardous Substances Data)

Upstream product

• 173442-36-9 methyl 6-oxo-1-(prop-2-yn-1-yl)-1,6-dihydropyridine-2-carboxylate 
• 30062-34-1 methyl 6-oxo-1,6-dihydropyridine-2-carboxylate 
• 19621-92-2 6-Hydroxypicolinic acid 
• 939055-78-4 6-oxo-1-(prop-2-yn-1-yl)-1,6-dihydropyridine-2-carboxylic acid 
• 99-98-9 4-amino-N,N-dimethylaniline 

Relevant articles and documents

Highly efficient and mild cascade reactions triggered by bis(triphenyl)oxodiphosphonium trifluoromethanesulfonate and a concise total synthesis of camptothecin

A mild and efficient cascade methodology is reported to construct variously substituted indolizino[1,2-b]quinolin-9(11H)-ones. Efficiently triggered by bis(triphenyl)oxodiphosphonium trifluoromethanesulfonate under mild conditions, this cascade achieved significant enhancements in chemical yields. Utilizing this highly efficient domino reaction followed by a Sharpless dihydroxylation, an eight-step total synthesis of camptothecln was accomplished from a known pyridine derivative in direct fashion with an overall yield of 47% and 95% ee.