939239-91-5Relevant articles and documents
Design, synthesis, and activity evaluation of GK/PPARγ Dual-target-directed ligands as hypoglycemic agents
Lu, Jianxun,Lei, Lei,Huan, Yi,Li, Yongqiang,Zhang, Lijing,Shen, Zhufang,Hu, Wenxiang,Feng, Zhiqiang
, p. 922 - 927 (2014)
Based on the multi-target strategy to treat type 2 diabetes mellitus (T2DM), glucokinase/peroxisome proliferator-activated receptor γ (GK/PPARγ) dual-target molecules were constructed by the rational combination of pharmacophores from known GK activators