93948-20-0

Basic information

• Product Name: BIS-(3-PHENYL-PROPYL)-AMINE
• Synonyms: BIS-(3-PHENYL-PROPYL)-AMINE;DI(3-PHENYL-1-PROPYL)AMINE
• CAS NO: 93948-20-0
• Molecular Formula: C₁₈H₂₃N
• Molecular Weight: 253.38
• Mol File: 93948-20-0.mol
• Article Data: 17

Chemical Properties

• Melting Point: 200-201 °C
• Boiling Point: 245 °C(Press: 35 Torr)
• Appearance: /
• Density: 0.982±0.06 g/cm3(Predicted)
• PKA: 10.47±0.19(Predicted)
• CAS DataBase Reference: BIS-(3-PHENYL-PROPYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS-(3-PHENYL-PROPYL)-AMINE(93948-20-0)
• EPA Substance Registry System: BIS-(3-PHENYL-PROPYL)-AMINE(93948-20-0)

Safety Data

• Hazardous Substances Data: 93948-20-0(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 2038-57-5 3-Phenylpropan-1-amine 
• 13372-81-1 (1E,2Z)-3-phenylacrylaldehyde oxime 
• 82166-21-0 methyl cyclohexane 
• 104-55-2 3-phenyl-propenal 
• 100-42-5 styrene 
• 50-00-0 formaldehyd 
• 23580-89-4 methyl-(3-phenyl-propyl)-amine 
• 506-59-2 N,N-dimethylammonium chloride 
• 51-80-9 bis-(dimethylamino)methane 
• 64-19-7 acetic acid 
• 14371-10-9 (E)-3-phenylpropenal 
• 637-59-2 1-Bromo-3-phenylpropane 
• 1885-38-7 cinnamic nitrile 

Downstream Products

• 150-59-4 alverine 

Relevant articles and documents

Sequential hydroaminomethylation/Pd-catalyzed hydrogenolysis as an atom efficient route to valuable primary and secondary amines

The facile synthesis of valuable primary and secondary amines is reported using a sequential procedure of hydroaminomethylation and Pd-catalyzed hydrogenolysis. The hydroaminomethylation reaction was catalyzed by a cationic Rh(I) iminopyridyl complex and the N-alkylated benzylamines were produced with high chemoselectivity, albeit as mixtures of linear and branched products. Performing the hydrogenolysis reaction using 10% Pd/C, provided access to valuable primary and secondary amines which have applications in the surfactant, pharmaceutical and polymer industries.

Pd/TiO2-Photocatalyzed Self-Condensation of Primary Amines to Afford Secondary Amines at Ambient Temperature

Symmetric secondary amines were synthesized by the self-condensation of primary amines over a palladium-loaded titanium dioxide (Pd/TiO2) photocatalyst. The reactions afforded a series of secondary amines in moderate to excellent isolated yields at ambient temperature (30 °C, in cyclopentyl methyl ether). Applicability for one-pot pharmaceutical synthesis was demonstrated by a photocatalytic reaction sequence of self-condensation of an amine followed by N-alkylation of the resulting secondary amine with an alcohol.

Chemoselective hydrogenation of nitriles to primary amines catalyzed by water-soluble transition metal catalysts

The water-soluble rhodium complex generated in situ from [Rh (COD)Cl]2 in aqueous ammonia has been revealed as a highly efficient catalyst for the hydrogenation of aromatic nitriles, to primary amines with excellent yields. The catalyst is also highly selective towards primary amines in the case of sterically hindered aliphatic nitriles. The catalytic system can also be recycled and re-used with no significant loss of activity.