94057-07-5

Basic information

• Product Name: Propanamide, N-[4-(2,3-dihydroxypropoxy)phenyl]-3-(methylthio)-
• CAS NO: 94057-07-5
• Molecular Formula: C13H19NO4S
• Molecular Weight: 285.364
• Mol File: 94057-07-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanamide, N-[4-(2,3-dihydroxypropoxy)phenyl]-3-(methylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-[4-(2,3-dihydroxypropoxy)phenyl]-3-(methylthio)-(94057-07-5)
• EPA Substance Registry System: Propanamide, N-[4-(2,3-dihydroxypropoxy)phenyl]-3-(methylthio)-(94057-07-5)

Safety Data

• Hazardous Substances Data: 94057-07-5(Hazardous Substances Data)

Upstream product

• 7031-23-4 3-(methylthio)propionyl chloride 
• 58754-71-5 3-(4-aminophenoxy)propane-1,2-diol 

Relevant articles and documents

Synthesis and antiallergic activity of dimethyl-2- (phenylcarbamoyl)ethylsulfonium p-toluenesulfonate derivatives

The derivatives of dimethyl-2-(phenylcarbamoyl)ethylsulfonium p- toluenesulfonates were synthesized and evaluated for antiallergic activity. The 2,3-dihydroxyethoxy group was introduced to the phenyl ring from the standpoint of lipophilicity and electronic effects of substituent. The IgE- induced rat passive cutaneous anaphylaxis (PCA) was inhibited by oral administration of several substituted 2-[(4- propoxyphenyl)carbamoyl]ethyldimethylsulfonium p-toluenesulfonate derivatives. Among them (±)-2-[N-[4-(3-ethoxy-2- hydroxypropoxy)phenyl]carbamoyl]ethyldimethylsulfonium p-toluenesulfonate (1a, IPD-1151T) was found to possess considerable activity in the PCA test, and it was launched as Suplatast tosilate in Japan.