94084-76-1 Usage
Description
6-(benzyloxy)nicotinic acid, also known as Benzyl 6-hydroxynicotinate, is a chemical compound belonging to the class of organic compounds known as benzyloxypyridines. It is a derivative of nicotinic acid and is recognized for its potential as a building block in the synthesis of various bioactive molecules and pharmaceutical drugs. This versatile intermediate is also valued for its antioxidant and anti-inflammatory properties, which position it as a promising candidate for the development of new therapeutic agents.
Uses
Used in Pharmaceutical Industry:
6-(benzyloxy)nicotinic acid is utilized as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its role in drug creation is multifaceted, as it aids in the production of a diverse range of medicinal compounds.
Used in Agrochemical Production:
In the agrochemical sector, 6-(benzyloxy)nicotinic acid serves as a precursor in the formulation of various chemical substances. Its application in this industry is instrumental in creating products that protect crops and enhance agricultural productivity.
Used in Chemical Substances Production:
Beyond its pharmaceutical and agrochemical applications, 6-(benzyloxy)nicotinic acid is also employed as a precursor in the production of a wide array of other chemical substances. Its versatility in chemical synthesis makes it an indispensable component in various industrial processes.
Used in Antioxidant and Anti-Inflammatory Agents Development:
Leveraging its inherent antioxidant and anti-inflammatory properties, 6-(benzyloxy)nicotinic acid is explored for its potential in the development of new therapeutic agents. Its capacity to combat oxidative stress and inflammation positions it as a valuable asset in the creation of innovative treatments for a variety of conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 94084-76-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,0,8 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 94084-76:
(7*9)+(6*4)+(5*0)+(4*8)+(3*4)+(2*7)+(1*6)=151
151 % 10 = 1
So 94084-76-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H11NO3/c15-13(16)11-6-7-12(14-8-11)17-9-10-4-2-1-3-5-10/h1-8H,9H2,(H,15,16)
94084-76-1Relevant articles and documents
First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump
Fontaine, Fanny,Hequet, Arnaud,Voisin-Chiret, Anne-Sophie,Bouillon, Alexandre,Lesnard, Aurélien,Cresteil, Thierry,Jolivalt, Claude,Rault, Sylvain
, p. 2536 - 2548 (2014/04/17)
Overexpression of efflux pumps is an important mechanism of bacterial resistance that results in the extrusion of antimicrobial agents outside the bacterial cell. Inhibition of such pumps appears to be a promising strategy that could restore the potency of existing antibiotics. The NorA efflux pump of Staphylococcus aureus confers resistance to a wide range of unrelated substrates, such as hydrophilic fluoroquinolones, leading to a multidrug-resistance phenotype. In this work, approximately 150 heterocyclic boronic species were evaluated for their activity against susceptible and resistant strains of S. aureus. Twenty-four hit compounds, although inactive when tested alone, were found to potentiate ciprofloxacin activity by a 4-fold increase at concentrations ranging from 0.5 to 8 μg/mL against S. aureus 1199B, which overexpresses NorA. Boron-free analogues showed no biological activity, thus revealing that the boron atom is crucial for biological activity. This work describes the first reported efflux pump inhibitory activity of boronic acid derivatives.
PYRROLIDINYL AND PIPERIDINYL COMPOUNDS USEFUL AS NHE-1 INHIBITORS
-
Page/Page column 147-148, (2010/04/03)
Disclosed are compounds of formula (I) and compositions of the present invention which are inhibitors of the sodium proton exchanger isoform-1 (NHE-I). Also disclosed are methods of using and making the same.
Pyridine amido derivatives
-
, (2008/06/13)
Disclosed are pyridine amido derivatives of the formula wherein X, Y, and R1 to R6 are as defined herein. These compounds are selective MAO-B inhibitors and are useful in treating diseases such as, for example, Alzheimer's and senile dementia. Also disclosed are pharmaceutical compositions containing such compounds and a method of preparing such compounds.
