940866-95-5Relevant articles and documents
Method for realizing insertion reaction of diazo ester compound and aniline molecule N-H through photocatalytic micro-channel
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Paragraph 0051-0061, (2021/11/10)
A homogeneous solution containing the aniline represented by the formula N, a derivative thereof and a diazo ester compound shown H is pumped into a microchannel reaction device with a light source to react to obtain I phenyl II benzene ethyl acetate deri
Method for constructing C-N bond through insertion reaction of non-metal catalyzed sulfur ylide and aromatic amine and application
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Paragraph 0012, (2020/10/20)
The invention relates to a method for constructing a C-N bond through an insertion reaction of non-metal catalyzed sulfur ylide and aromatic amine and application. According to the method, water is used as a reaction solvent, and sulfur ylide is subjected to an N-H insertion reaction under mild conditions to construct a C-N bond. As a way of constructing a C-N bond, the method overcomes the defects of traditional use of metal catalysts or oxidants. On the basis of the method, various alpha-amino acid ester derivatives can be obtained by using different aromatic amines as substrates. Accordingto the method, the raw materials are easy to obtain, use of a metal catalyst, an oxidizing agent and an organic solvent is avoided, and the method is a mild, effective and environment-friendly methodfor preparing the alpha-amino acid ester and has wide application prospects.
Carbene X[sbnd]H bond insertions catalyzed by copper(I) macrocyclic pyridine-containing ligand (PcL) complexes
Tseberlidis, Giorgio,Caselli, Alessandro,Vicente, Rubén
supporting information, p. 1 - 5 (2017/03/01)
A catalytic system comprising copper(I) and macrocyclic pyridine-containing ligands (Pc-L) proves capable of promoting carbene Si[sbnd]H bond insertions using diazo compounds as the carbene source. This catalytic system showed broad scope and a remarkable robustness as indicated by high TON numbers (up to 30000). Moreover, the use of enynones as carbene sources proved also feasible in hydrosilane insertion using this catalytic system. Finally, the insertion in O[sbnd]H and N[sbnd]H bonds of phenols and anilines, respectively, has been also demonstrated.