94143-83-6 Usage
Description
5,6,7,8-Tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline is an organic compound that serves as a key reactant in the synthesis of various bioactive molecules. Its unique structure, featuring a tetrahydroisoquinoline core fused with a dioxolane ring, endows it with potential applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Synthesis:
5,6,7,8-Tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline is used as a reactant in the synthesis of Crispine-A and Dysoxyline, two bioactive compounds with potential therapeutic applications. Its role in these syntheses highlights its importance in the development of new drugs and pharmaceutical agents.
Used in Chemical Research:
In addition to its pharmaceutical applications, 5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline may also be utilized in chemical research for the exploration of novel reactions and the synthesis of other complex organic molecules. Its unique structure and reactivity make it a valuable tool for advancing the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 94143-83-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,1,4 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 94143-83:
(7*9)+(6*4)+(5*1)+(4*4)+(3*3)+(2*8)+(1*3)=136
136 % 10 = 6
So 94143-83-6 is a valid CAS Registry Number.
94143-83-6Relevant articles and documents
Aryl radical cyclizations of 1-(2′-bromobenzyl)isoquinolines with AIBN-Bu3SnH: Formation of aporphines and indolo[2,1-a]isoquinolines
Orito, Kazuhiko,Uchiito, Shiho,Satoh, Yoshitaka,Tatsuzawa, Takashi,Harada, Rika,Tokuda, Masao
, p. 307 - 310 (2007/10/03)
(matrix presented) Radical cyclization of alkoxy-substituted 1-(2′-bromobenzyl)-3,4-dihydroisoquinolines 1 with AIBN-Bu3SnH gave 6a,7-dehydroaporphines 2 preferentially. A steric repulsion between the respective alkoxy groups at the 7- and 3′-positions gave 5,6-dihydroindolo[2,1-a]isoquinolines 3 in a disfavored 5-endo cyclization mode. Radical cyclizations of the related substrates, such as 1-(2′-bromobenzoyl)isoquinolines or 1-(2′-bromo-α-hydroxybenzyl)isoquinolines, were also found to give the corresponding oxoaporphines or oxyaporphines.