94166-58-2

Basic information

• Product Name: 2-AMINOPYRIDINE
• Synonyms: PYRIDIN-2-YLAMINE;TIMTEC-BB SBB004394;AKOS 91158;AKOS BBS-00004471;AMINOPYRIDINE, 2-;2APY;2-PYRIDINYLAMINE;A-PYRIDYLAMINE
• CAS NO: 94166-58-2
• Molecular Formula: C₇H₉N₃O₃
• Molecular Weight: 183.17
• EINECS: 207-988-4
• Mol File: 94166-58-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 54-58 °C(lit.)
• Boiling Point: 204-210 °C(lit.)
• Flash Point: 198 °F
• Appearance: /
• Density: 1.328 g/cm³
• Vapor Pressure: 0.000174mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-AMINOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOPYRIDINE(94166-58-2)
• EPA Substance Registry System: 2-AMINOPYRIDINE(94166-58-2)

Safety Data

• Hazard Codes: T
• Statements: 21-25-36/37/38
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2671 6.1/PG 2
• WGK Germany: 3
• RTECS: US1575000
• F: 8-21
• Hazardous Substances Data: 94166-58-2(Hazardous Substances Data)

Usage

General Description

2-Aminopyridine is a chemical compound with the formula C5H6N2. It consists of a pyridine ring with an amino group attached at the 2-position. It is a highly versatile compound and is used in various chemical and pharmaceutical applications. 2-Aminopyridine is a key intermediate in the synthesis of pharmaceuticals, including anti-inflammatory and analgesic drugs. It is also used as a building block for the production of herbicides and dyestuffs. Additionally, it has potential use in organic synthesis as a catalyst and ligand, as well as in the production of agrochemicals. Due to its broad range of applications, 2-aminopyridine is a valuable compound in the chemical industry. However, it is important to handle this chemical with care, as it can be toxic and hazardous if not properly managed.

InChI:InChI=1/C7H9N3O3/c1-8-7-5(10(11)12)3-4-6(9-7)13-2/h3-4H,1-2H3,(H,8,9)

Upstream product

• 38533-61-8 2-chloro-6-methoxy-3-nitropyridine 
• 74-89-5 methylamine 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 124-41-4 sodium methylate 
• 33742-70-0 6-chloro-N-methyl-3-nitropyridin-2-amine 

Downstream Products

• 172648-25-8 5-[4-(5-methoxy-3-methyl-3H-imidazo[4,5-b]pyridin-2-ylmethoxy)benzyl]-3-triphenylmethylthiazolidine-2,4-dione 
• 90817-34-8 3-amino-6-methoxy-2-(methylamino)-pyridine 

Relevant articles and documents

Design, Synthesis, and Fungicidal Activity of Novel Imidazo[4,5-b]pyridine Derivatives

A series of novel imidazo[4,5-b]pyridine derivatives were designed and synthesized. The structures of all the newly synthesized compounds were identified by spectroscopic data NMR, MS, and elemental analysis. Bioassay showed that the compounds exhibited potent fungicidal activities against Erysiphe graminis, Puccinia polysora, and so forth. Particularly, 2-chloro-5-((5-methoxy-2-(2-(trifluoromethyl)phenyl)-3H-imidazo[4,5-b]pyridin-3-yl)methyl)thiazole (9b) displayed fungicidal potency against P.?polysora. Its EC50 value: 4.00?mg/L is comparable with that of tebuconazole. The structure–activity relationship for the target compounds is discussed.

Heterocyclic compounds having anti-diabetic activity and their use

Compounds of formula (I): STR1 [wherein: X represents an unsubstituted or substituted indolyl, indolinyl, azaindolyl, azaindolinyl, imidazopyridyl or imidazopyrimidinyl group; Y represents an oxygen or sulfur atom; Z represents a 2,4-dioxothiazolidin-5-ylidenylmethyl, 2,4-dioxothiazolidin-5-ylmethyl, 2,4-dioxooxazolidin-5-ylmethyl, 3,5-dioxooxadiazolidin-2-ylmethyl or N-hydroxyureidomethyl group; R represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a hydroxy group, a nitro group, an aralkyl group or a unsubstituted or substituted amino group; and m is an integer of from 1 to 5] have hypoglycemic and anti-diabetic activities.