94169-64-9

Basic information

• Product Name: Benzaldehyde, 3,5-bis(1-methylethoxy)-
• CAS NO: 94169-64-9
• Molecular Formula: C13H18O3
• Molecular Weight: 222.284
• Mol File: 94169-64-9.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3,5-bis(1-methylethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3,5-bis(1-methylethoxy)-(94169-64-9)
• EPA Substance Registry System: Benzaldehyde, 3,5-bis(1-methylethoxy)-(94169-64-9)

Safety Data

• Hazardous Substances Data: 94169-64-9(Hazardous Substances Data)

Upstream product

• 94169-63-8 (3,5-diisopropoxyphenyl)methanol 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 75-30-9 2-iodo-propane 
• 26153-38-8 3,5-dihydroxybenzaldehyde 
• 75-26-3 isopropyl bromide 
• 94169-62-7 methyl 3,5-di-isopropoxybenzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 29654-55-5 5-(hydroxymethyl)benzene-1,3-diol 
• 951776-82-2 C₁₆H₂₄O₄ 

Downstream Products

• 94169-65-0 2-iodo-3,5-di-isopropoxybenzaldehyde 
• 216700-46-8 (E)-1-(2-hydroxy-4,6-diisopropoxyphenyl)-3-(3,5-diisopropoxyphenyl)propenone 
• 587870-62-0 α-(4-methoxyphenyl)-m,m-diisopropoxycinnamic acid 
• 587870-58-4 α-(4-isopropoxyphenyl)-m,m-diisopropoxycinnamic acid 
• 937175-34-3 C₁₇H₂₄O₄ 
• 951776-59-3 C₂₁H₂₄O₅ 
• 951776-61-7 C₃₀H₃₆O₇ 
• 951776-62-8 C₄₅H₄₄O₇ 
• 951776-63-9 C₃₆H₃₄O₇ 
• 937175-41-2 C₁₅H₂₂O₃ 
• 352287-02-6 (E)-(S)-3-{4-[3-(3,5-diisopropoxy-phenyl)-allyloxy]-phenyl}-2-ethoxy-propionic acid ethyl ester 
• 501-36-0 (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol 
• 65728-21-4 5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol 
• 61434-67-1 cis-resveratrol 

Relevant articles and documents

Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2

Resveratrol (3,5,4′-trihydroxylstilbene) has been proposed to elicit a variety of positive health effects including protection against cancer and cardiovascular disease. The highest affinity target of resveratrol identified so far is the oxidoreductase enzyme quinone reductase 2 (QR2), which is believed to function in metabolic reduction and detoxification processes; however, evidence exists linking QR2 to the metabolic activation of quinones, which can lead to cell toxicity. Therefore, inhibition of QR2 by resveratrol may protect cells against reactive intermediates and eventually cancer. With the aim of identifying novel inhibitors of QR2, we designed, synthesized, and tested two generations of resveratrol analogue libraries for inhibition of QR2. In addition, X-ray crystal structures of six of the resveratrol analogues in the active site of QR2 were determined. Several novel inhibitors of QR2 were successfully identified as well as a compound that inhibits QR2 with a novel binding orientation.

PYRIDINE, QUINOLINE AND PYRIMIDINE DERIVATIVES

This invention is concerned with compounds of the formula wherein A, R1 to R5 are as defined in the specification and G is a pyridine, quinoline or pyrimidine group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES

This invention relates to compounds of the formula wherein X is O or NR8, Y is CR7 or N, and R1 to R8 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.