94190-88-2

Basic information

• Product Name: 1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone
• Synonyms: 1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone;NSVIDCOUQPRFCB-UHFFFAOYSA-N
• CAS NO: 94190-88-2
• Molecular Formula: C₁₄H₁₈O₆
• Molecular Weight: 282.28912
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 94190-88-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone(94190-88-2)
• EPA Substance Registry System: 1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone(94190-88-2)

Safety Data

• Hazardous Substances Data: 94190-88-2(Hazardous Substances Data)

Usage

Description

1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone is an off-white solid that serves as a crucial reactant in the synthesis of various organic compounds.

Uses

Used in Pharmaceutical Industry:
1-[2-Hydroxy-4,6-diMethoxy-3-(1-oxopropoxy)phenyl]-1-propanone is used as a reactant for the preparation of Stigmatellin A (S686780), a compound with potential pharmaceutical applications.
As a key intermediate in the synthesis of Stigmatellin A, this compound plays a significant role in the development of new drugs and therapeutic agents. Its unique chemical structure allows for further functionalization and modification, making it a valuable building block in the creation of novel pharmaceutical compounds.

Upstream product

• 500-99-2 3,5-dimethoxyphenol 
• 94190-87-1 1-(2-Hydroxy-4,6-dimethoxy-3-propionylphenyl)-1-propanone 

Downstream Products

• 276690-21-2 2-[(3S,4S,5S,6R)-7-Benzyloxy-4,6-dimethylheptyl]-5,7-dimethoxy-8-methoxymethoxy-3-methyl-4H-1-benzopyran-4-one 
• 276690-20-1 (4S,5S,6S,7R)-8-Benzyloxy-5,7-dimethoxy-4,6-dimethyloctanoic acid 3,5-dimethoxy-2-methoxymethoxy-6-propionylphenyl ester 
• 91682-96-1 stigmatellin A 
• 276690-22-3 (2R,3S,4S,5S)-7-[5,7-dimethoxy-8-methoxymethoxy-3-methyl-4-oxo-4H-2-chromenyl]-2,4-dimethoxy-3,5-dimethylheptanol 
• 276690-11-0 1-[2-hydroxy-4,6-dimethoxy-3-(methoxymethoxy)phenyl]propan-1-one 
• 94190-89-3 1-(2,3-Dihydroxy-4,6-dimethoxyphenyl)propan-1-one 

Relevant articles and documents

Diastereo- and enantioselective total synthesis of stigmatellin A

Stigmatellin A (1) isolated from the myxobacterium Stigmatella aurantiaca is a powerful inhibitor of electron transport in mitochondria and chloroplasts. The first highly diastereo- and enantioselective total synthesis of this important natural product is