942047-64-5 Usage
Description
Piroxicam-d3, a cyclooxygenase inhibitor, is a deuterated analog of the nonsteroidal anti-inflammatory drug (NSAID) Piroxicam. It is a pale yellow solid with chemical properties that make it a clinically useful NSAID for various applications.
Uses
Used in Pharmaceutical Industry:
Piroxicam-d3 is used as a cyclooxygenase inhibitor for its anti-inflammatory, analgesic, and antipyretic properties. It is particularly effective in treating conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Used in Research and Development:
Piroxicam-d3 is utilized as a deuterated analog in research and development for studying the mechanism of action, metabolism, and pharmacokinetics of Piroxicam. Its deuterium labeling allows for enhanced sensitivity and specificity in analytical techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy.
Used in Drug Development and Design:
Piroxicam-d3 serves as a valuable tool in drug development and design, providing insights into the structure-activity relationships and optimization of NSAIDs. Its deuterated nature aids in understanding the role of specific functional groups and their impact on the drug's efficacy and safety profile.
Check Digit Verification of cas no
The CAS Registry Mumber 942047-64-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,0,4 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 942047-64:
(8*9)+(7*4)+(6*2)+(5*0)+(4*4)+(3*7)+(2*6)+(1*4)=165
165 % 10 = 5
So 942047-64-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)/i1D3
942047-64-5Relevant articles and documents
Synthesis of deuterium-labelled meloxicam and piroxicam
Balssa, Frederic,Bonnaire, Yves
, p. 207 - 210 (2007)
Four step syntheses of deuterium-labelled meloxicam and piroxicam from saccharin via selective CD3I alkylation are described. Labelled oxicams are of great interest for qualitative and/or quantitative isotope dilution-mass spectrometry, coupled with liquid chromatography, currently performed in anti-doping and forensic laboratories. Copyright
