94223-54-8

Basic information

• Product Name: 2-Butanone, 4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-
• CAS NO: 94223-54-8
• Molecular Formula: C13H14N2O3
• Molecular Weight: 246.266
• Mol File: 94223-54-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-(94223-54-8)
• EPA Substance Registry System: 2-Butanone, 4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-(94223-54-8)

Safety Data

• Hazardous Substances Data: 94223-54-8(Hazardous Substances Data)

Upstream product

• 25877-54-7 methyl 4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl ether 
• 26562-24-3 3-bromo-2-methoxypropene 

Downstream Products

• 94223-61-7 4-Methoxy-benzoic acid N'-(5-methyl-4,5-dihydro-3H-pyrrol-2-yl)-hydrazide 
• 94223-73-1 (4aR,8aS)-3-(4-Methoxy-phenyl)-5,6,7,8,8a,9-hexahydro-4aH-[1,2,4]triazolo[4,3-a]indole 
• 94223-73-1 (4aR,8aR)-3-(4-Methoxy-phenyl)-5,6,7,8,8a,9-hexahydro-4aH-[1,2,4]triazolo[4,3-a]indole 
• 94223-58-2 2-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-cyclohexanone 
• 94223-69-5 2-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-cyclohexylamine 
• 94223-65-1 3-(4-Methoxy-phenyl)-5-methyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazole 

Relevant articles and documents

SYNTHESIS OF CYCLOPENTANO-s-TRIAZOLES BY THE INTRAMOLECULAR RING TRANSFORMATION OF 1,3,4-OXADIAZOLES

Cyclopentano-s-triazoles were synthesized by intramolecular ring transformation starting from γ-keto-1,3,4-oxadiazoles 5 and 9.The required functionality for this intramolecular reaction was established by (i) the reaction of lithiated 2-methyl-1,3,4-oxadiazole 4 with the methyl enol ether of α-bromo ketones followed by hydrolysis; (ii) reductive amination of γ-ketones 5 and 9 to further reorganized hydrazide 7 and γ-amino-1,3,4-oxadiazole 9 with NaBH3CN; and (iii) pyrolysis of 7 and 9 at 280 deg C (5 mmHg) to the cyclopentano-s-triazoles 8 and 11.By the same treatment, the S-connected analogue 2 afforded the desired fused s-triazole 17.