94242-81-6 Usage
Description
(R)-BoroVal-(+)-Pinanediol-CF3CO2H, also known as Trifluoroacetate, is a chemical compound that serves as an impurity in Bortezomib (B675700). Bortezomib is the first proteasome inhibitor approved by the US FDA for the treatment of multiple myeloma, a type of blood cancer. (R)-BoroVal-(+)-Pinanediol-CF3CO2H is characterized by its unique structure, which includes a hexahydro-3a,5,5-trimethyl-alpha-(1-methylethyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine backbone and a trifluoroacetate group.
Uses
Used in Pharmaceutical Industry:
(R)-BoroVal-(+)-Pinanediol-CF3CO2H is used as an impurity in the production of Bortezomib, a proteasome inhibitor, for the treatment of multiple myeloma, a blood cancer. Its presence in Bortezomib is significant as it targets the ubiquitin-proteasome pathway, a crucial cellular process involved in the regulation of protein homeostasis. As a reversible inhibitor of the 26S proteasome, a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells, Bortezomib plays a vital role in the management of multiple myeloma.
Check Digit Verification of cas no
The CAS Registry Mumber 94242-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,2,4 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 94242-81:
(7*9)+(6*4)+(5*2)+(4*4)+(3*2)+(2*8)+(1*1)=136
136 % 10 = 6
So 94242-81-6 is a valid CAS Registry Number.
